C4 Flashcards
Notriptyline
A. Antidepressant (adrenergic uptake inh)
B. Inhibits reupake of serotonin at the neuronal membrane
C. Depression, chronic pain, sleep disorders, IBS, diabetic neuropathy, agitation
Amitriptyline
A.antidepressant (adrenergic uptake inh)
B. Inhibits reuptake of NE and serotonin
C. Depression, chronic pain, sleep disorders, diabetic neuropathy
Paroxetine
A. Antidepressant (serotonin uptake inh) - selective
B. Inhibit reupake of serotonin at the neuronal membrane
C. Stress disorders, depression, dementia, agitation, menstrual problems
Escitalopram
A. Antidepressant (serotonin uptake inh)
b. Inhibits the reupake of serotonin at the neuronal membrane
C. Major depressive disorder, anxiety disorder, dementia
Sertraline
A. Antidepressant (serotonin uptake inh)
B. Inhibit the reupake if serotonin at the presynaptic membrane
C. Major depressive disorder, stress disorder, panic attacks, premature ejaculation, vascular headaches
Mirtazapine
A. Antidepressant (H1R blocker)
B. Acts as antagonist at Central presynaptic alpha R- inhibit negative feedback to the presynaptic nerve - cause an increase in NE release
C. Major depressive disorders
Duloxetine
A. Antidepressant (adrener. uptake inh)
B. Inhibitor of neuronal serotonin and NE reupake and less potent inhibitor of D reupake
C. Major depressive disorder, anxiety disorders, neuropathic pain, urinary incontenence
Venlafaxine
A. Antidepressant agent
B. Inhibits reupake of serotonin and NE
C. Major depressive disorder, anxiety, panic attacks, vasomotor symptoms, neuropathic pain
Bupropion
A. Antidepressant (dopamine uptake inh)
B. Inhibit the neuronal reupake of dopamine, NE and serotonin
C. Depression, aid for smoking cessation
Agomelatine
A.antidepressant agent
B. Acts as agonist of melatonin R and antagonist of 5HT20 R
C. Major depressive disorder
Methylphenidate
A. Dopamine uptake inhib
B. Blocks dopamine uptake in Central adrenergic neurons by blocking Dopamine transport or carrier proteins
C. Behaviour stabiliser, ADHD
Atomoxetine
A.antisepreasant (adrenergic uptake inh)
B. Selective inhibition of the presynaptic NE transporter
C. Attention deficit/ hyperactivity disorder
Baclofen
A. Muscle relaxant
B. Inhibits both mono synaptic and post synaptic reflexes at the spinal level
C. Multiple sclerosis, symptoms if spasticity
Tolperisone
A. Muscle relaxant
B. Acts at the reticular formation by blocking voltage gated Na and Ca channels
C. Damage of pyramidal tract, multiple sclerosis, myelopathy, encephalomyeltis
Caffeine natri benzoas
A. Caffeine derivate
B. Stimulates CSN and CV system
C. Asthma, hypersomnia, apnea of prematurity
