Cáncer de pulmón Flashcards

1
Q

Variedad histológica de cáncer de pulmón con alteración de p53, RB, deleción de cromosoma 3 y amplificación de MYC

A

Carcinoma de células pequeñas

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2
Q

Origen celular del carcinoma de células pequeñas

A

Celulas progenitras neuroendocrinas del pulmón

Celulas de Kulchitsky

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3
Q

Fenómeno de Azzodardy puede sugerir 2 cosas

A

Neoplasia neuroendocrina y linfoma

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4
Q

IHQ para confirmar una neoplasia neuroendocrina

A

CD56+

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5
Q

Marcadores para adenocarcinoma

Cáncer de pulmón

A

TTF-1
Napsina 1

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6
Q

IHQ para saber si es mesotelioma

A

Positivo a:
* Calretinina
* Citoqueratinas
* Podoplaninas

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7
Q

Cancer de pulmón epidermoide es más común en

A

Hombres fumadores

Presentación central

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8
Q

Marcadores epiteliales para cancer de pulmon epitelial

A

p63 y p40

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9
Q

Deleciones del cromosoma 3p y 9p sugieren…

Tipo de cáncer de pulmón

A

Epitelial

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10
Q

Origen de la neoplasia de células grandes

A

Origen neuroendocrino que invade pleura y pared torácica

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11
Q

Mutaciones que indican la posibilidad de terpia blanco en cáncer de pulmón

A

EGFR
KRAS
EML4 - ALK

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12
Q

Tumor de pancoast es un tumor en:

Localización

A

Tumor en el ápice del pulmon

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13
Q

Sindrome de horner presenta

3 cosas

A
  • Tosis
  • Miosis
  • Anhidrosis
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