Carbohydrates and Carbohydrate Metabolism Flashcards
Glycosidic linkage
the bond between two sugar molecules
Covalent bond formed in a dehydration reaction that requires enzymatic catalysis
Glycolysis
Universal first step in glucose metabolism
Glucose molecule is oxidized and split into two pyruvate molecules, producing a net surplus of 2 ATP and producing 2 NADH
Hexokinase
catalyzes the first step in glycolysis
G6P feedback-inhibit hexokinase
Phosphofructokinase (PFK)
The key biochemical valve controlling the flow of substrate to product in glycolysis, and the conversion of F6P to F1,6bP
Lactate produced after long periods of strenuous activity is transported to the liver where it is
converted back to pyruvate
Cori cycle
Liver deals with lactate from muscle
Oxidative decarboxylation
a molecule is oxidized to release CO2 and produce NADH
Prosthetic group
cofactor is very tightly or covalently bound to the enzyme
Prosthetic group
cofactor is very tightly or covalently bound to the enzyme
Two goals of ETC/oxidative phosphorylation
reoxidize all the electron carriers reduced in glycolysis, PDC, and the Krebs Cycle
Store energy in the form of ATP in the process
Gluconeogenesis
occurs when dietary sources of glucose are unavailable and when the liver has depleted its stores of glycogen and glucose
Requires 4 ATP, 2 GTP, and 2 NADH
Reciprocal control
the same molecule regulates two enzymes in opposite ways
Products of the Pentose Phosphate Pathway
Glyceraldehyde-3-phosphate, Fructose-6-Phosphate, Ribose-5-phosphate, NADPH,