Cardiology Flashcards
What is the expected max heart rate of a given adult? What HR should be achieved in stress test?
220 - age
Expected to reach 85% during stress test
Pharmacological Stress Test
Adenosine / Dipyridamole - causes coronary vasodilation; if already fully dilated at rest then when who system is dilated there will be relatively less flow
Dobutamine - inc myocardial oxygen demand (inc HR, contractility and BP)
Indications for CABG
1- three vessel disease (> 70% stenosis of ea)
2- LAD > 50% (supplies 2/3 heart)
3- LV dysfunction
CAD Mgt
Should all be on ASA
Beta blockers - reduce HR / oxygen demand of heart
Nitrates - vasodilation for symptomatic relief
Ca Channel Blockers - second line if not fully managed on beta and nitrates
If co-existing CHF - ACE and / or diuretic
Prinzmetal Angina
Transient coronary vasospasm
Transient ST elevation during chest pain episode
Diagnosis - definitively by coronary angiography; give ergonovine or acetylcholine to vasoconstrict –> spasm
Dec lipids, smoking cessation, Ca channel blockers, nitrates
Cardiac Enzymes
Always order if chest pain w/ cardiac suspicion
Troponin - inc in 3-5 hrs; peak at 24-48 hrs; inc for 5-14 days
CK-MB - inc in 4-8 hrs; peak at 24 hrs but returns to normal by 48-72 hrs so good for detecting recurrent MI
Serial - check q 8 hrs for 24 hrs
Std MI Tx
MONA + beta + statin + heparin
M - morphine (dec pain and venous dilation)
O - oxygen
N - nitrates (dilation for symptoms relief)
A - ASA (prevent platelet aggregation on top of existing thrombus) + ACE (dec mortality)
Beta - dec mortality; dec oxygen demand; dec remodeling after MI
Statin - (atorvastatin); take long term to reduce risk repeat event
Heparin - LMWH (enoxaparin)
When to use dual anti-platelet in CAD
30 days after bare metal stent
12 mo for drug-eluting stent
Dressler Syndrome
wks to months after MI
Immunologically based pericarditis (fever, malaise, leukocytosis, pleuritis)
Tx = ASA
Mgt of CHF Pts (long-term therapy and what to monitor)
Drugs (for systolic) -
- ACE + diuretic (symptomatic relief of edema)
- May add beta blocker (metoprolol, bisprolol, carvedilol); dec remodeling
- Nitrates
- Digoxin (inotrope - use if EF < 40%); must check level periodically
Monitor -
- Wt gain at ea visit
- Exercise intolerance
- Amount of peripheral edema
- Electrolytes, BUN, Cr, digoxin level if using
Digoxin Toxicity
GI - nausea and vomiting; dec appetite
Cardiac - ectopic beats, AV block, A fib
Neuro - disorientation, visual disturbances
PVCs
Conduction thru ventricular muscles; slower; wide QRS
Only concerning if also have underlying structural heart disease
Couplet = 2 PVCs in a row Bigeminy = sinus then PVC Trigeminy = 2 sinus then PVC
A Fib
No p waves
Irregularly irregular RR intervals (between QRS complexes)
If stable - rate control (beta or Ca channel blocker), then convert, anticoagulation w/ warfarin
Echo to check for mural thrombus before electrical conversion
Atrial Flutter
atrial rate 250-300 but refractory period of AV node means only 1 of every 2-3 p waves –> QRS
Sawtooth of p waves w/ QRS after every 2-3 p waves (esp in inferior leads - II, III, aVF)
WPW
Accessory path from atria to ventricles
Short PR interval & delta waves before QRS
AVOID DRUGS THAT DEC AV NODE BECAUSE THIS MAY ACCELERATE THRU ACCESSORY PATH (no digoxin, verapamil or beta blockers)