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REPRO > Case 2 > Flashcards

Case 2 Flashcards

1
Q

It is involved in steroid biosynthesis

a. AR
b. CYP3A4
c. CYP17
d. HPC1

A

C

AR & CYP3A4 - deactivation of testosterone

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2
Q

Protective factors against prostate cancer include the following, except:

a. isoflavonoid genistein
b. alpha-linoleic acid
c. lycopene
d. isothiocyanate sulforaphane

A

B

polycyclic aromatic hydrocarbons

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3
Q

It is the predominant therapy to reduce the future risk of a prostate cancer diagnosis

a. vitamin E
b. selenium
c. 5a-reductase inhibitors
d. dutasteride

A

C

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4
Q

It is the most important source of sensory nerve signals for initiating the male sexual act

a. vas deferens
b. seminal vesicles
c. scrotum
d. glans penis

A

D

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5
Q

Most common organic cause of erectile dysfunction

a. neurogenic
b. vasculogenic
c. endocrinologic
d. diabetic
e. psychogenic

A

B

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6
Q

The following cause erectile dysfunction by suppressing gonadotropin production, except:

a. serotonin
b. estrogen
c. GnRH agonists
d. H2 agonists
e. spironolactone

A

A

serotonin - decrease dopamine enhanced libido, arousal, and erection

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7
Q

Which of the following antidepressant/antipsychotic drugs exhibit the highest risk for sexual dysfunction?

a. mirtazapine
b. paroxetine
c. bupropion
d. nefazodone

A

B

and escitalopram

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8
Q

The following are classified as causes of ED are due to failure to initiate, except:

a. neurogenic
b. vasculogenic
c. endocrinologic
d. psychogenic

A

B

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9
Q

The age-related decline in testosterone is due to defects at all
levels of the hypothalamic-pituitary-testicular axis, except:

a. Pulsatile GnRH secretion is attenuated
b. LH response to GnRH is reduced
c. Testicular response to LH is impaired
d. Insulin resistance

A

D

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10
Q

It is the zone that is least likely for BPH and cancer to develop

a. central zone
b. peripheral zone
c. transitional zone
d. lateral zone

A

A

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11
Q

It is the largest zone which contains 70% of the prostate’s glandular tissue

a. central zone
b. peripheral zone
c. transitional zone
d. lateral zone

A

B

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12
Q

It typically undergo benign prostatic hyperplasia (BPH)

a. central zone
b. peripheral zone
c. transitional zone
d. lateral zone

A

C

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13
Q

It is where putative intraepithelial neoplasia and prostate cancer predominate

a. central zone
b. peripheral zone
c. transitional zone
d. lateral zone

A

B

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14
Q

Variant of prostate cancer that occurs in 70% of the cases with a characteristic feature of outer basal cell layer typical of benign glands is absent

a. acinar prostatic adenocarcinoma
b. squamous cell carcinoma
c. colloid carcinoma of the prostate
d. small cell carcinoma

A

A

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15
Q

Also called mucinous adenocarcinoma of the prostate

a. acinar prostatic adenocarcinoma
b. squamous cell carcinoma
c. colloid carcinoma of the prostate
d. small cell carcinoma

A

C

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16
Q

It is the most aggressive variant of prostate cancer

a. acinar prostatic adenocarcinoma
b. squamous cell carcinoma
c. colloid carcinoma of the prostate
d. small cell carcinoma

A

D

17
Q

It is rapidly eliminated from the blood by glomerular filtration with estimated half-life of 12-18h

a. Total PSA
b. Free PSA
c. Intact PSA
d. Human kallikrein 2

A

B

18
Q

Cut-point for prostate biopsy

a. <4 ng/mL
b. >4 ng/mL
c. 4-10 ng/mL
d. >10 ng/mL

A

B

19
Q

The following are included in the algorithm to produce 4Kscore, except:

a. four specific kallikrein immunoassays
b. px’s age
c. DRE results
d. prior positive biopsy status

A

D

20
Q

The fallowing are factors associated with incontinence after radical prostatectomy, except:

a. older age
b. urethral length
c. surgeon’s skill and experience
d. quality of erections before surgery

A

D

21
Q

Testosterone levels with outcomes in older men is positively associated with the following, except:

a. physical function
b. sexual desire
c. muscle mass
d. major depression

A

D

22
Q

The uses of neoadjuvant hormone therapy before radiation therapy are the following, except:

a. decrease size of the prostate
b. decrease exposure of normal tissue to full-dose radiation
c. decrease local control
d. decrease rate of systemic failure

A

C

23
Q

Which of the following’s efficacy is not affected by alcohol?

a. sildenafil
b. vardenafil
c. tadalafil
d. avanafil
e. two of the options

A

E

C and D

24
Q

TNM Classification of tumor that is identified by needle biopsy

a. T1
b. T1a
c. T1b
d. T1c

A

D

25
Q

TNM Classification that is defined by tumor that involves both lobes

a. T2
b. T2a
c. T2b
d. T2c

A

D

REPRO (4 decks)

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