CD markers and cytokines

Question 2

Activated macrophages secrete TNF-alpha that can

Answer 2

Kill a variety of cells

Question 3

CD45

Answer 3

Marker present on B cells and their precursors and can serve as a signal-transduction molecule on the membrane of T cells

Question 4

CD35 & CD21

Answer 4

Receptors on B cells for certain complement products

Question 5

CD16, a membrane receptor for the Fc region of the IgG molecule

Answer 5

NK cells

Question 6

CD32

Answer 6

A receptor for IgG on the surface of B cells

Question 7

CD40

Answer 7

Marker present on the surface of B cells that interact with the CD40 ligand on the surface of T h cells. This interaction is critical for the survival of the stimulated B cell and their differentiation into effector and memory cells

Question 8

CD3

Answer 8

Marker associated with TCR

Question 9

CD28

Answer 9

Receptor present on the surface of T h cells responsible for the co-stimulatory B7 family molecules present on B cells and other APCs

Question 10

Activated macrophages secrete IL-1 to

Answer 10

Activate lymphocytes

Question 11

Have TCRs and express NK1.1 that interacts with CD1

Answer 11

NKT cells

Question 12

CD4

Answer 12

Marker present on the surface of T h cells and is class-II restricted

Question 13

Class II MHC molecules

Answer 13

Permit the B cell to function as APC

Question 14

Activity of NK cells is increased by

Answer 14

IL-2, IL-12 & IF gamma

Question 15

CD80 & CD86

Answer 15

Molecules that interact with CD28 and CTLA-4 on the surface of T cells . They are used as the co-stimulatory signal for the activation of T h cells

Question 16

CD8

Answer 16

Marker present on the surface of Tc cells and is class-I restricted

Question 17

CD4 & CD25

Answer 17

Markers present on the surface of T reg cells

Question 18

What is the signature cytokine for T h1 cells?

Answer 18

Interferon gamma

Question 19

What is the signature cytokine for T reg cells?

Answer 19

Interleukin-10 & Tgf betta

Question 20

Killer-cell inhibitory receptor (KIR)

Answer 20

NK cells

Question 21

Activated macrophages secrete IL-1 +IL-6 +TNF-alpha that

Answer 21

Promote fever by affecting the thermoregulatory center in the hypothalamus

Question 22

What is the signature cytokine for T h2 cells?

Answer 22

Interleukin-4 (for the present)

Question 23

Activated by cytokines released by T h cells(IFN-gamma)

Answer 23

NK cells