Cell Death Flashcards
What is apoptosis.
Programmed cell death when damage is less severe. Requires atp and uses capsases enzymes.
What is oncosis?
Death associated with cell membrane rupture occurs with severe membrane damage.
Passive cell death. Oncotic cells swell up as digestive enzymes are oroduced increasing osmotic pressure.
What are the advantages if apoptosis?
Process doesn’t induce inflammation, only affects one cell rather than large number of adjacent cells. Components readily recyclable.
What is necrosis.
Tissue death in a live organism.
What is an infarct?
Necrosis due to a lack of oxygen usually due to blockage if an end artery
What is gangrene?
Necrotic tissue that is discoloured.
Dry gangrene: affects extremities, black due to lack of oxygen. No bacteria.
Wet gangrene: bacterial infection of necrotic tissue, putrification.
What happens to infarcts in the cns?
They are liquefactic or colliquative. Tissue is a vicious liquid mass.
What is autolysis?
Death if tissue on a dead organism. Stopped by formaline.
What necrosis is key to tb?
Caseous necrosis. Grey cottage cheese. Soft white proteinaceous cell mass. Myobacterium hide in macrophages and the enzymes released by dying macrophages causes necrosis.
