Cellular Communication Flashcards
What percentage of the body’s total body water is intracellular?
65%
What percentage of the body’s total body water is extracellular?
30%
What percentage of the body’s total body water is transcellular?
2-3%
What percentage of the body’s total body water is interstitial?
25%
What percentage of the body’s total body water is plasma?
8%
What is the extracellular concentration of each of Na+ and Cl- ?
150mM
What is the intracellular concentration of K+?
100mM
At what voltage range are Na+v channels inactivated?
+35 to -90mV, delayed
At what voltage range are Na+v channels are resting?
-90mV
At what voltage range are Na+v channels are activated?
-90 to +35mV
What are K2P channels activated by?
pH, stretch, volatile anaesthetics (TREK1),arachidonic acid
Do Gs channels cause relaxation or contraction?
Contraction, via increased cAMP.
Do Gi channels cause relaxation or contraction?
Relaxation, via decreased cAMP.