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HLST 110 > centenarians > Flashcards

centenarians Flashcards

1
Q

what is a centenarian?

A

a person who lives to or beyond the age of 100 years.

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2
Q

the term centenarian is associated with ___________.

A

longevity

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3
Q

super-centenarian?

A

a person who has lived to the age of 110 or more,

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4
Q

super centenarian is something only achieved by _____ in 1,000 centenarian.

A

1

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5
Q

according to recent estimate how much proportion of us population is centenarian?

A

10-20 centenarians per 100,000 population in us

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6
Q

who is the oldest validated Canadian ever? and what did she claimed as key to longevity.

A

Marie-Louise Meilleur(118 yrs)
1880-1998
hard work = key to longevity.

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7
Q

name the French supercentenarian from arles?

A

Jeanne Calment , passed away in 122 years and 164 days in 1997

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8
Q

health and lifestyle routines of Jeanne calment

A

took care of her skin with olive oil and puff powder
cycling until 100 bday
gymnastic on wheelchair, flexing stretching
washed herself with flannel cloth rather than shower
mad herself fruit salads
consistent routine
went to bed early, woke up early

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9
Q

what was the age of the man in bigger Saskatchewan who was a centenarian and what was his lifestyle

A

107, 4 bottles red wine almost every day

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10
Q

how many centenarians in 2011 did Canada, Japan, Russia and (France,italy,uk) had per 100,000

A

canada- 17.4
Japan- 37
russia- 4
France, Italy and uk- higher centenarian rates than Canada

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11
Q

what was the life expectancy in 1920s and 2000-2002?

A

1920s- male-59 yrs
females-61 yrs
2000-2002- male-77 yrs
females-82 yrs

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12
Q

how many centenarians were there in Canada during 2001

A

3795

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13
Q

how many centenarians in Canada in 2022?

A

13,484

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14
Q

what was Canada’s population in 2011 compared to 1911

A

1911- 7.2 million
2011-33.5 million

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15
Q

when could have the 2011 centenarians be born and started life?

A

born in 1911 or before,
children during ww1,
entered labour force, started family in great depression 1930s,
older adults during baby boom period, retired in 70s

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16
Q

what year was the Great Depression

A

1930s

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17
Q

baby boom period?

A

1946-1965

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18
Q

centenarians present in Canada from 2018-2022 according to statistics?

A

2018-9,457
2019-10,581
2020-11,815
2021-12,906
2022-13,484

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19
Q

which province had the highest life expectancy during 20the century and finally the highest. no. of centenarians?

A

Saskatchewan, 31 per 100,000 in 2011.

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20
Q

the lowest no. of centenarians according to statistics 2011?

A

3 terr- Yukon, northwest territories, Nunavut (4.7 Per 100,000)

21
Q

average centenarians in Canada during 2011 statistics?

A

17.4 per 100,000

22
Q

current trend in ______ in us is affecting life longevity.

A

obesity

23
Q

if ________ rates continue to decline in the next decade the number of people belonging to 2011 and reaching 100 in 2111 is much higher.

A

mortality rates

24
Q

diff life expectancies in statistics show ________ of life expectancy.

A

variations

25
Q

what were the 2 blips caused in life expectancy?

A

2017- opioid pandemic
2020- covid 19

26
Q

what blip affected 2019 cohort?

A

2017- opioid pandemic

27
Q

who reach the age of 100 more? men/women

A

women

28
Q

2011 census counted ______ women and ______ men as centenarians and the corresponding sex ratio was ___ women for every 100 men?

A

4,870 women and 955 men
500 women per 100 men

29
Q

in Canadian population up to the age of 26, more ___ were present and after that more ______.

A

upto 26- men
after 26- women

30
Q

by age 65 in Canada their were _____ women for 100 men and by age 80 _____ many women for 100 men

A

125
170

31
Q

what is a fountain of youth

A

a spring that supposedly restores the health of anyone who drinks or bathes in its waters.

32
Q

__________, a spanish explorer was looking for fountain of youth aka ________ to cure his_______ but discovered _______ in _______

A

Ponce de león
waters of Bimini
aging
florida
1513

33
Q

factors to living to be 100?

A

1.inherited genes or your own biology
2.where you live
3.the choices you make
4.eating a plant based diet, quitting smoking, reducing stress, exercising, and getting enough sleep. Drinking coffee or tea, practicing conscientiousness, finding joy, and limiting your alcohol intake also benefit your long-term health and well-being.

34
Q

what is a “blue zone”?

A

an area characterized by extreme longevity in the sardinia island.
highest concentration of male centenarians

35
Q

who introduced blue zone?

A

Michel Poulain and Giovanni pes

36
Q

what does the diff lifestyle o people in blue some include?

A

regular low level activity
plant-prioritized diet
eat until 80% full
intergenerational family
strong friendship structure
reason for waking up in the morning
pause for nature 24 hours 1 per week

37
Q

what are the 9 common diets told by dan buettner to live 100+ after studying blue zone community?

A

1.move naturally(no exercise but perform such activity no need of exercise just physical movement0
2.right outlook(sense of purpose)ikigai
3.eat wisely(plant, 80%rule)
4.connection with loved ones, belong, right tribe
family, not smoking, plant-slant diet, constant moderate physical activity, social engagement, legumes.

38
Q

what are the common longevity myths told by dan buettner?

A

1.if I try really hard, can live upto 100.
2.treatments exist that can slow aging.

39
Q

do sibling of centenarians live longer as well?

A

potential genetic traits of longevity
97th percentile-95+

40
Q

what are some researched longevity ideas?

A

1.genetic immunological diff 🧬
2. genetic influence on insulin regulation
3.calorie restricted diet-works in rodents

41
Q

what are the benefits of calorie restricted diet in human?

A

beneficial effects against obesity, insulin resistance, inflammation, oxidative stress, left ventricular diastolic dysfunction, reduced cholesterol, blood pressure, and risk factors for cardiovascular disease. Including: Yeast, worm, fruit fly, rodent, primate

42
Q

how did 30%dietary restriction affect n adult 20 yr old rhesus monkey?

A

1.reduced age related death(66)
2.incidence of neoplasia and cardiovascular disease was 50%lower
3.none developed diabetes or pre diabetes
4.major reduction in body fat mass
5.higher insulin sensitivity
6.reduced inflammation and oxidative damage
(4,5,6 also noticed in rodents)
7.immune senescence, sarcopenia and brain atrophy of grey matter were reduced

43
Q

what are some possible downsides of dietary restriction?

A

reduced resistance to infection or reduced affect of wound healing

44
Q

what were the adaptions observed in dietary restricted rodents?

A

major reduction In body fat mass, higher insulin sensitivity, reduced inflammation and oxidative damage

45
Q

what hormonal adaptations observed in dietary-restricted rodents are seen in humans?

A

increased adiponectin, reduction in triiodothyronine, testosterone and insulin

46
Q

dietary restriction reduced the ____________ of the carotid arteries which is a risk factor for cardiovascular disease.

A

intimal-media thickness

47
Q

what effect does extreme dietary restriction has on one’s health?

A

amenorrhea, infertility, sarcopenia, osteoporosis, and immune deficiencies

48
Q

______, the TOR inhibitor extends the mouse life span is an ______ for human and may not prove good for human health.

A

rapamycin
immunosuppressant

49
Q

genetic deletion of the ________ or of the downstream_______ in mice extends life span and induces a broad-spectrum improvement in health

A

GH receptor
S6 Kinase

HLST 110 (7 decks)

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