Cervical Cancer

Question 1

what is the part that becomes malignant

Answer 1

the walls of the cervix

Question 2

Etiology/risks

Answer 2

HPV
-strains 6/11 cause genital warts
strains 16/18 account for cervical cancer

Early age sex
multiple partners
smoking
HX of std

Question 3

Patho: how does the malignancy progress

Answer 3

in a widening fashion

Question 4

what type of cell origin is cervical cancer

Answer 4

squamous cell origin

Question 5

there is an initial WHAT That occurs

Answer 5

dysplasia (pre cancer lesion)

Question 6

later on that dysplasia then…

Answer 6

becomes invasive into the deeper tissue layers (years between pre cancer stage and invasive stage)

Question 7

what does CIN stand for

Answer 7

cervical intraepithelial neoplasia

Question 8

what are the levels of cervical intraepithelial neoplasia

Answer 8

CIN1: mild dysplasia
CIN2: moderate
CIN3: severe and carcinoma in situ

Question 9

how does cervical cancer metastasize

Answer 9

via lymphatics

Question 10

Diagnosis

Answer 10

Screening tool: PAP smear to see if squamous cells have changed in appearance *dysplasia
colposcopy if dysplasia is present

Question 11

Manifestations

Answer 11

vaginal discharge
bleeding
metrorrhagia 
frequent menses
late: pain

Question 12

Treatment

Answer 12

early: excision of the cells undergoing dysplasia
Invasive: radiation and surgery
Cryosurgery
Conization
Laser: bring about necrosis
Advanced: radical hysterectomy