Cervical/Vulvar/Ovarian cancer Flashcards
What is the usual presentation of vulva cancer?
Pain Itch Bleeding Lump/ulcer Over 60
What are some risk factors associated with vulva cancer?
Intraepithelial neoplasia or cancer at other lower genital tract site
Lichen sclerosis
Smoking
Immunosuppression
Which lymph nodes are involved in vulva cancer?
Inguinal
Upper femoral
Pelvic
What is vulvar intraepithelial neoplasia and its major risk?
Abnormal proliferation of squamous epithelium
Can progress to carcinoma
Is vulvar cancer usually HPV related in younger or older women?
Younger
What is an important consideration in biopsy of vulvar cancer?
Depth of invasion
What are some risk factors commonly associated with cervical cancer?
HPV related Multiple sex partners Intercourse at early age Older age of partner Smoking
What are the usual symptoms for cervical cancer?
Abnormal vaginal bleeding Post coital bleeding Intermenstrual bleeding Discharge Pain
What are the most common kinds of cervical cancer?
Squamous carcinoma
Adenocarcinoma
Which investigations are used to stage cervical cancer?
PET
CT
MRI
What are the main options for cervical cancer treatment?
Excision
Radical hysterectomy
Combined chemoradiation
What are some genetic associations of ovarian cancer?
HNPCC
BRCA1
BRCA2
How does serous cystadenoma present histologically?
Impressionist wavy with a dark border at the top
How does serous carcinoma present histologically?
Low grade kind of has a bunch of different coloured patches that are split up by white stuff and the whole thing surrounded by stuff that looks kind of dense
High grade is liked cracked desert
How does ovarian cancer usually present?
Vague Indigestion Altered bowel habit Pain Bloating Discomfort Weight gain Pelvic mass
