CH-22 Aminoglycosides RxPREP MUST KNOWS Flashcards

1
Q

Aminoglycoside coverage

A

Gentamicin/Tobramicin/Amikacin

Gram negatives (Including Pseudomonas)

Synergy for Gram Pos
Staphylococci n Enterococci

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2
Q

Aminoglycoside Good NEWs

A

Kill gram negative and synergistic with betalactams for gram pos

low resistance

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3
Q

Aminoglycosides BAD NEWS

A

Ototoxic

Nephrotoxic

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4
Q

Aminoglycoside Smart idea!

A

Concentration dependent

HIGH dose less often

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5
Q

Aminoglycoside warnings

A

Use with other renal toxic drugs

(amphotericin B, cisplatin, polymyxins, cyclosporine, loop diuretics, NSAIDs, radiocontrast dye, tacrolimus and vancomycin)

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