CH-22 Cephalosporin RxPRE MUST KNOWS Flashcards

1
Q

1st generations coverage

A

IV: Cefazolin

PO: Cephalexin

Staphylococci

Streptococci

PEK (Gram neg rods)

  • Proteus, E. Coli, Klebsiella

Mouth anaerobes (Gram pos)

  • Peptostreptococcus
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2
Q

2nd Generation coverage

A

Cefuroxime (Ceftin)

Better gram neg coverage (HNPEK)

Haemophillus, Neisseria, Proteus, E. Coli, Klebsiella

Cefotetan and Cefoxitin

anaerobic coverage

B-frag

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3
Q

3rd Generation coverage

A

Group 1

IV: Ceftriaxone

PO: Cefdinir

Less staph coverage

BETTER Strep coverage

Group 2

IV Ceftazidime, Ceftazidime/Avi

Pseudomonas

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4
Q

4th Generation coverage

A

IV Cefipime

BROAD SPECTRUM:

Gram Pos

Gram Neg HNPEK

Haemophillus, Neiseria, Proteus, E. Coli, Klebsiella

Gram Neg CAPES

Citrobacter, Acintobacter, Provedencia, Enterobacter, Serattia

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5
Q

1st generation cephaloporins

A

Cefazolin (Ancef)

Cephalexin (Keflex) 250-500mg Q6-12

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6
Q

2nd generation cephaloporins

A

Cefuroxime (Ceftin)

Cefotetan (Cefotan)

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7
Q

3rd generation cephaloporins (Group 1)

A

Cefdinir (Omnicef)

Ceftriaxone (Rocephin)

Cefotaxime

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8
Q

3rd generation cephaloporins (group 2)

A

Ceftazidime (Fortaz)

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9
Q

4th generation cephaloporins

A

Cefepime

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10
Q

Cephalosporin class effects

A

No eneterococcus coverage

No atypical coverage

beta-lactam allergy!!

Risk of Seizures!!

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11
Q

1st generation cephaloporins coverage outpatient

A

Keflex

Strep throat, MSSA Skin infx

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12
Q

2nd generation cephaloporins coverage outpatient

A

Cefuroxime

AOM

CAP

Sinus infections

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13
Q

3rd generation cephaloporins coverage outpatient

A

Cefdinir (Omnicef)

CAP

Sinus infx

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14
Q

1st generation cephaloporins coverage inpatient

A

Cefazolin

surgical prophylaxis

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15
Q

2nd generation cephaloporins coverage inpatient

A

Cefotetan, Cefoxitin

surgical prophylaxis (GI)

Cefotetan (DISULFRAM)

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16
Q

3rd generation cephaloporins coverage inpatient

A

Ceftriaxone, Cefotaxime

  • CAP
  • SBP
  • menigitis
  • pyelonephritis

DO NOT USE IN NEONATES

Ceftriaxone no renal dose adjustment

17
Q

Cephalosporins that cover pseudomonas

A

Ceftazidime (3rd gen)

Cefipime (4th gen)