Chapter 12

Question 1

characteristics of ideal anti microbial drug

Answer 1

reasonably priced, microbicidal rather than microbistatic, does not disrupt the hosts health, remains potent long enough to act

Question 2

chemotherapeutic drug

Answer 2

any chemical used in the treatment of a disease

Question 3

synthetic drugs

Answer 3

made entirely in the lab through chemical reactions

Question 4

semisynthetic drugs

Answer 4

chemically modified in the lab after being isolated from natural resources

Question 5

antibiotics

Answer 5

produced by the natural metabolic processes of some microorganisms that can inhibit or destroy other microorganisms (fungi & bacteria)

Question 6

anti microbial

Answer 6

all inclusive term for any antimicrobial drug

Question 7

narrow spectrum

Answer 7

limited spectrum and only affect a little range of microbes

Question 8

broad spectrum

Answer 8

extended spectrum that affect a wide variety of microbial types

Question 9

Cell wall synthesis, plasma membrane, and nucleic acid are all…

Answer 9

bactericidal

Question 10

protein synthesis & folic acid synthesis are..

Answer 10

bacteriostatic

Question 11

cell wall synthesis drug examples

Answer 11

penicillins, glycopeptides, and miscellaneous G+

Question 12

Plasma membrane drug examples

Answer 12

polypeptides G-

Question 13

nucleic acid drug examples

Answer 13

fluoroquinolones G+ & G-
Rifamycibs G+ & mycobacteria

Question 14

protein synthesis drug examples

Answer 14

aminoglycosides G-
Tetracyclines G+ & G-
macrolides G+ $ G-

Question 15

folic acid synthesis drug examples

Answer 15

sulfonamides G+ & G-

Question 16

beta-lactation drugs

Answer 16

penicillins & beta-lactamases

Question 17

non-beta-lactate drugs

Answer 17

glycopeptides & miscellaneous

Question 18

the process of selecting an antimicrobial drug

Answer 18

identify the agent

testing for the drug susceptibility of microbes

patient factors

Question 19

major side effects

Answer 19

organ toxicity

allergic responses

alternation of microbiota

Question 20

drug resistance

Answer 20

gene transfer

gene mutations

Question 21

therapeutic index

Answer 21

you want it high so you can take a low dose