Chapter 13

Question 1

What is complex one called?

Answer 1

NADH-Q oxidoreductase

Question 2

What is complex two called?

Answer 2

succinate-Q reductase

Question 3

What is complex three called?

Answer 3

Q-cyt c oxidoreductase

Question 4

What is complex four called?

Answer 4

Cyt c oxidase

Question 5

Complex 1

Answer 5

catalyzes electron transfer from NADH to Q coupled with the transfer of four H+ across the membrane

Question 6

Complex 2

Answer 6

Converts succinate to fumarate which forms FADH2 and electrons are passed from Fe-S centers to Q

Question 7

Complex 3

Answer 7

Electrons are passed from QH2 to cytochrome c by complex 3.

Question 8

Complex 4

Answer 8

Reduces oxygen to water

Question 9

Importance of ATP synthase in the respiratory chain

Answer 9

forms ATP (see page 132 to see the mechanism!)

Question 10

Barbiturates

Answer 10

inhibit electron transport via complex 1 by blocking the transfer from Fe-S to Q

Question 11

Antimycin A and dimercaprol

Answer 11

Inhibit the respiratory chain at complex 3

Question 12

H2S, CO, CN

Answer 12

Inhibit complex 4 and arrest respiration

Question 13

Malonate

Answer 13

competetive inhibitor of complex 2

Question 14

Oligomycin

Answer 14

blocks oxidation and phosphorylation by blocking the flow of protons through ATP synthase

Question 15

Uncouplers

Answer 15

dissociate oxidation in the respiratory chain from phosphorylation