Chapter 14 Flashcards
Two steps for using an electrochemical proton gradient to synthesize ATP
- energy released by electron transport is used to pump protons across membrane
- energy stored in the proton gradient is harnessed by ATP synthase to make ATP
chemiosmotic coupling
mechanism that uses the energy stored in a transmembrane proton gradient to drive an energy-requiring process
functions of the mitochondris
production of ATP
regeneration of NAD+
precursors for synthesis of amino acids, nucleotides, fatty acids
synthesis of heme and iron-sulfur clusters
cell signaling
generation of reactive oxygen species
regulation of apoptosis
is the inner or outer mitochondrial membrane more permeable?
outer
site of oxidative phosphorylation
inner mitochondrial matrix
final electron acceptor of the electron transport chain
O2
oxidative phosphorylation definition
membrane-based process in which ATP formation is driven by the transfer of electrons derived from food molecules to molecular oxygen
respiratory enzyme complex definition
set of proteins in the inner mitochondrial membrane that facilitates the transfer of high-energy electrons from NADH to oxygen while pumping protons into the intermembrane space
function of NADH dehydrogenase complex
accepts electrons from NADH
ATP synthase defintion
abundant membrane-associated enzyme complex that catalyzes the formation of ATP from ADP and inorganic phosphate during oxidative phosphorylation and photosynthesis
how many molecules of ATP does ATP synthase produce for one revolution
3
electrochemical proton gradient is used for _______ and _______
generation of ATP
transport of selected metabolites and proteins across the inner mitochondrial membrane
what mobile carrier do FADH2 molecules pass their electrons to
ubiquinone
Direct products of glycolysis
2 NADH
2 ATP
direct products of pyruvate oxidation to acetyl CoA (two per glucose)
2 NADH