Chapter 5 Flashcards
1
Q
Primary structure
A
Sequence of amino acids in a polypeptide chain
2
Q
Alpha helix
A
- complete turn has about 3.6 residues
- stability from hydrogen bonds
- proline can only be accommodated by the first turn
3
Q
Beta sheet
A
Zig zag or pleated pattern
-parallel or antiparallel
4
Q
Antiparallel beta sheet
A
Hydrogen bonds run parallel to polypeptide backbone
5
Q
Beta turn
A
Involved 4 aminoacyl residues
6
Q
Loops
A
Contain more than 4 aminoacyl residues
7
Q
Monomeric
A
One polypeptide chain
8
Q
Dimeric
A
2 polypeptide chains
9
Q
Homodimers
A
Two copies of the same polypeptide chain
10
Q
Heterodimers
A
The 2 chains differ
11
Q
Chaperones
A
Prevent aggregation
hsp70 binds short sequences of hydrophobic amino acids that emerge while a new polypeptide is forming
12
Q
Aggregates
A
Complexes of partly unfolded polypeptides
13
Q
Collagen
A
- glycine, hydroxyproline, and hydroxylysine
- triple helix has 3.3 residues per turn
14
Q
Globular proteins
A
Compact, roughly spherical molecules
