Chapter 6 DNA structure Flashcards

1
Q

Name the place where DNA is located in a eukaryotic cell.

A

Nucleus, chloroplasts, mitochondria

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2
Q

Identify the components of a chromosome from a eukaryotic cell.

A

DNA double helix and histone proteins

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3
Q

Explain homologous.

A

A pair of chromosomes that have the same size, shape and genes at the same locations

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4
Q

Explain sister chromatid.

A

One of the two identical copies of a single chromosome, formed by replication and connected by a centromere

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5
Q

Describe the DNA in the mitochondria and chloroplasts of eukaryotic cells.

A

Is similar to the single, circular chromosomes in prokaryotic cells.

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6
Q

Explain what a karyotype is.

A

It displays the number and structure of chromosomes at cell division - metaphase.

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7
Q

what is metaphase

A

Happens during cell division

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8
Q

what is a gene

A

region/s of DNA that are made up of nucleotides
-Unit of heredity
-transmits information from one generation to the next

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9
Q

Explain RNA replication.

A

-Single stranded
-Has uracil in place of thymine
-Has ribose sugar instead of deoxyribose sugar
-Functions as a structural part of ribosomes and in protein synthesis

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10
Q

Leading strand of DNA

A

made continuously

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11
Q

Lagging strand of DNA

A

Made in fragments

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12
Q

Plasmids

A

Small circular piece of DNA found in bacteria which can replicate independently of the cells chromosomes.
-often contains antibiotic resistant genes.

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13
Q

The type of chemical bond that holds strands of DNA together

A

Hydrogen bonds between complementary nitrogenous bases

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14
Q

pathogenic

A

causes disease, bacteria

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15
Q

Function and structure of a gene

A

-Codes for a polypeptide, segment of DNA
-Unit of heredity, transmits information from one generation to the next

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16
Q

Genome

A

-All genetic material in an organism or cell
-bigger than gene
-In eukaryotes includes DNA in mitochondria and chloroplasts and chromosomes in nucleus

17
Q

DNA replication process

A

Double helix seperates into two individual strands. Results in two double strands of DNA identical to the original molecule

18
Q

Replication fork

A

Between unwound single strands of DNA and the intact double helix,
-between DNA helicase and DNA polymerase

19
Q

DNA

A

double stranded molecule that occurs bound to proteins (histones) in chromosomes in the nucleus

20
Q

DNA replication

A

process by which DNA makes a copy of itself during cell division

21
Q

Process of DNA replication: DNA polymerase

A

DNA polymerase joins free nucleotides to the growing new complementary strand

22
Q

Process of DNA replication: Helicase

A

DNA helicase unzips the double stranded DNA (parental strand) by breaking weak hydrogen bonds between nucleotides

23
Q

Structure of DNA

A

Nucleotides are composed of:
1. 5 carbon sugar
2. negatively charged phosphate group
3. A base - an organic nitrogen

24
Q

DNA in prokaryotes

A

DNA is single and circular, lies in direct contact with the cytoplasm

25
Q

DNA in eukaryotes

A

DNA found in the membrane bound nucleus, chloroplasts and mitochondria

26
Q

5’ to 3’ DNA replication

A

DNA is only synthesised in the 5’ to 3’ direction

27
Q

Chromatin and its structure

A

Complex of proteins and DNA in eukaryotic chromosomes

-Structure: chromosomes are single, long double helix coiled around histones unless cell is actively dividing

28
Q

Chromosomes and its structure

A

-X shaped
-Have undergone replication in readiness for cell division

-Structure: Composed of DNA, linear arrays in eukaryotes