Chapter 7

Question 1

DNA Polymerase 1 is found in what and responsible for what?

Answer 1

Is principally involved in the repair of damaged DNA in both prokaryotic and eukaryotic cells.

Question 2

DNA Polymerase III is found in what and responsible for what?

Answer 2

In bacteria, it is the major polymerase responsible for DNA replication.

Question 3

DNA Polymerase (ε, δ, and α) is found in what and responsible for what?

Answer 3

In Eukaryotic cells, responsible for replication of Nuclear DNA.

Question 4

DNA Polymerase γ

Answer 4

In the mitochondria of Eukaryotic cells, responsible for replication of mitochondrial DNA.

Question 5

Two Fundamental Properties of DNA Polymerase.

Answer 5

1. All polymerases synthesize DNA in the 5’ to 3’ direction, adding a dNTP to the 3’ hydroxyl group of the growing chain.
   2.

Question 6

Two Fundamental Properties of DNA Polymerase.

Answer 6

1. All polymerases synthesize DNA in the 5’ to 3’ direction, adding a dNTP to the 3’ hydroxyl group of the growing chain.
2. DNA polymerases can add new deoxyribonucleotides only to a preformed primer strand that is hydrogen-bonded to the template. They can not initiate DNA synthesis de novo.