Chapter 7: Protein Behavior Flashcards
an oligomeric enzyme whose biological activity is affected by other substances binding to it
-they change the enzyme’s activity by altering the conformation of its 4⁰ structure
allosteric enzyme
a substance that modifies the behavior of an allosteric enzyme
allosteric effector
What is feedback inhibition?
formation of final product inhibits its continued production
Inactive precursor of an enzyme where cleavage of one or more covalent bonds transforms it into the active enyzme
zymogen
Which amino acids are key to covalent catalysis?
Chymotrypsin cleaves on the C-side of hydrophobic amino acids
His
Asp
Gly
Ser
Which two amino acids must be close to each other in the active site for chymotrypsin to function?
Ser-195
His-57
Serine oxygen is a (nucleophile/acid) and attacks the carbonyl group of peptide bonds.
Nucleophile
a nonprotein substance that takes part in an enzymatic reaction and is regenerated for further reaction
coenzyme
-Zn2+, Fe2+
a nonprotein substance that takes part in an enzymatic reaction and is regenerated for further reaction
coenzyme
-Zn2+, Fe2+
These vitamins are coenzymes involved in amino acid transfer from one molecule to another
-important in amino acid biosynthesis
B6 vitamins
What are involved in transanimation reactions?
pyridoxal and pyridoxamine phosphates
What is transanimation?
a reaction which uses pyridoxal and pyridoxamine phosphates in the transfer of amino groups
