chemo

Question 1

alkylating agents

- cyclophosphamide, ifosfamide

Answer 1

hemorrhagic cystitis, encephalopathy associated with ifosfamide administration

Question 2

cytotoxic

-bleomycin

Answer 2

pulmonary fibrosis

Question 3

antimetabolites

-5-fluorouracil, capecitabine, methotrexate, cytarabine

Answer 3

diarrhea, mucositis, hand-foot-mouth syndrome, neutropenia

Question 4

type II topoisomeriase inhibitors

-doxorubicin, daunorubicin, idarubicin

Answer 4

cardiovascular toxicity

Question 5

vinca alkaloids

- vincristine, vinblastine

Answer 5

peripheral neuropathy

Question 6

taxanes

- paclitaxel

Answer 6

peripheral neuropathy

Question 7

platinum-based

-cisplatin, carboplatin, oxaliplatin

Answer 7

renal dysfunction, ototoxicity

Question 8

topoisomerase inhibitors

-etoposide

Answer 8

asthenia, stomatitis, diarrhea

Question 9

radiation

Answer 9

myocardial ischemia, pericarditis, myocarditis, valvular heart disease

Question 10

HER2 inhibitors

- trastuzumab

Answer 10

HFrEF

Question 11

VEFG inhibitors

-Bevacizumab

Answer 11

HTN, venous or arterial thromboembolic events, bowel perforation, bleeding

Question 12

TKIs

- dasatinib

Answer 12

pulmonary hypertension

Question 13

mTOR inhibitors

- everolimus

Answer 13

mucositis, skin toxicity