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Contact Lens 1 > CL Solutions (Logan) > Flashcards

CL Solutions (Logan) Flashcards

1
Q

What defines Plasma Tx?

A

NOT a true coating, removes residue from manufacturing process, imparts ultra clean lens, and CAN enhance initial wettability, comfort, and vision

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2
Q

What defines Tangible Hydra-PEG?

A

PERMANENT coating design to improve comfort, made of hydrophilic polymers, 90% water, inc. wettability, lubricity, deposit resistance; DO NOT want to use abrasive or alcohol cleaners for these

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3
Q

GP lens care components, what are some?

A

Wetting/soaking, cleaner, and rewetting/re-lubricating drops (big emphasis on wettability)

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4
Q

4 Major functions of wetting and soaking agents?

A
  1. Maintain lens hydration
  2. Disinfection
  3. Mechanical buffer/cushion between lens and cornea
  4. Temporarily enhance surface wettability
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5
Q

For temporarily enhancing surface wettability - what are we doing to achieve this/parameters to achieve this?

A

-We are trying to make it into a hydrophilic end. When we store it dry, it leans toward a hydrophobic end on the surface.
-Ionicity
-And these wetting agents typically contain: Methylcellulose derivatives (viscous) and PVA (polyvinyl alcohol), which are water soluble, non-viscous, non-toxic

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6
Q

Lens cleaners, what types?

A

Daily Cleaners, Non-Abrasive Daily Cleaner, Abrasive Daily Cleaners, Combo cleaning & Disinfection solution, Rinsing Agent, and Enzyme & protein removers

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7
Q

Daily Cleaners GP vs SCL?

A

More import in GP wear bc lenses need to last longer and surfaces readily attract oils from eye/eye creams, soaps, makeup remover etc

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8
Q

In Daily Cleaners, surfactant/detergents plus friction rub on the lenses do what?

A

Remove environmental and tear film debris (make up, mucoprotein, lipids, etc)

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9
Q

When to use Daily Cleaners?

A

After lens removal in the evening - enhances disinfection, debris more easily removed. Improves wettability

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10
Q

Is rub necessary with Daily Cleaners?

A

Yes, rub 2-3 drops of DC in palm of hand for 15-30 second because digital pressure/friction helps remove deposits (not excessively bc can warp/break lens); clean in palm with L-R motion (not fingers and not circular motion bc can break or change lens parameters)

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11
Q

What are non-abrasive daily cleaners?

A

May contain nonabrasive surfactant (detergent) agents

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12
Q

What can non-abrasive daily cleaners NOT be used with?

A

Hydra-PEG lenses (Example: Lobob Optimum Extra Strength Cleaner RED CAP)

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13
Q

What makes up an abrasive daily cleaner?

A

Surfactant plus small particles of polymer to increase friction

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14
Q

Abrasive daily cleaners (list of things to know about them?)

A
  • Highly effective
  • Patients may alter power (inc minus, dec CT)
  • Newer products have smaller particle size (less risk)
  • May be contraindicated hyper-DK lens materials, plasma tx, or hydra-PEG
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15
Q

Example of abrasive daily cleaner?

A

Boston Advance/Original Conditioning Solution RED CAP

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16
Q

What is Combo cleaning & Disinfection solution?

A

Surfactant soaking - dissolve deposits during overnight soaking cycle must be rinsed prior to lens insertion

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17
Q

Example of combo cleaning & disinfection solution?

A

Lobob Optimimum CDS RED CAP; also NOT okay for Hydra-PEG

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18
Q

What are rinsing agents?

A

Saline, either preserved or non-preserved; multi-purpose solution

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19
Q

Enzyme and protein removers are …?

A

Beneficial adjunct to daily cleaner and prevent cumulative build-up of protein &/or lipids; can be separate products or include MPS
Examples: Boston One-step liquid enzymatic clener, progent protein remover, boston simplus

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20
Q

What do rewetting and re-lubricating drops do?

A

Rewet lens surface, stabilize tear film, rinse away trapped debris under the lens, and breakup loosely attached deposits

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21
Q

All in one/ Muti-purpose (Hydra-PEG compatible)

A

Cleaning, disinfect, wetting/conditioning
Examples: Boston simplus multi-action solution, Menicon Unique pH, Alcon Clear Care –>* Cannot be placed directly into eye from bottle before neutralization

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22
Q

For MPS/Ain1 if label says conditioner, wetting, rinsing agent then?

A

OK for lens application (no need to rinse before applying to eye); **NOT the case for Optimum CDS or ESC + Clear Care

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23
Q

For a GP lens care sequence, how long to soak overnight?

A

At least 4-6 hours with all-in-one or conditioner/wetting agent

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24
Q

What about for Optimum CDS?

A

Solution for at least 4 hours and DO NOT apply to eye Rinse off thoroughly

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25
Q

What should the active ingredients in solution preservatives do? (5 things)

A
  1. Disinfect
  2. Prevent toxic rxns
  3. Avoid adverse effects on lenses
  4. Wettability/parameters
  5. Enhance tear film compatibility
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26
Q

Preservative sensitivity symptoms include? Decrease or increase over time of use?

A

Dryness, redness/burning, itching, lens awareness. These will increase over time

27
Q

Signs of sensitivities to a solution?

A

Injection, follicles and papillae, tear film debris, mucus strands, superficial punctate staining

28
Q

Bactericidal preservatives vs Bacteriostatic preservatives?

A

Kills microorganisms vs Inhibits microorganism growth

29
Q

Preservatives!

A

Coming note cards

30
Q

Benzalkonium Chloride (BAK)

A

Quaternary ammonium compound

31
Q

BAK is effective against..? And used in a majority of opthalmic preparations for what type of solutions?

A

Wide spectrum of bacteria and fungi; GP solutions, is NOT used in SCL solutions due to binding properties that can be toxic

32
Q

BAK effectiveness is enhanced with?

A

EDTA

33
Q

Chlorhexidine

A

Bactericidal soln for GP and SCLs (Greater conc in GP; has limited binding capacity w/ GP lenses); it is not used that often in SCL soln

34
Q

Chlorhexidine is relatively ineffective against what? And limited effectiveness in?

A

Serratia; limited eff in yeast and fungi

35
Q

How is efficacy improved for Chlorhexidine? Addition of _____ or _____

A

EDTA or Thimerosal

36
Q

Chlorhexidine examples?

A

B&L Boston Line: Simplus (MPS), Original Conditioning, Advance Conditioning (lower conc than original)

37
Q

Thimerosal

A

Bactericidal; organic mercurial compound, slow acting but good broad spectrum

38
Q

Thimerosal is ineffective against what (in low conc.)?

A

Ineffective against Pseudomonas

39
Q

Why is Thimerosal not used much now?

A

Due to sensitivities like burning sensation, redness, SPK

40
Q

Ethylenediamine tetra acetate (EDTA)

A

Chelating agent, not a true preservative

41
Q

Why is EDTA used in combo with other agents? What is this combo used against especially? MOA?

A

Synergistic effects of combo; used especially against Pseudomonas; MOA - disrupts cell walls of bacteria to give preservative better efficacy

42
Q

Polyaminopropyl biguanide (PAPB/Dymed)

A

Used in GP and SCL solns (Conc 30-50x greater in GP solns)

43
Q

More or less effective than Chlorhexidine against Serratia?

A

PAPB has Greater efficacy

44
Q

PAPB is effective against ?

A

Acanthamoeba

45
Q

Examples of PAPB?

A

Boston Advance Conditioning Solution, Boston Simplus, B&L soft lens products

46
Q

Polquaternium-1 (polyquad)

A

Similar molecular structure to chlorhexidine (So, bactericidal); used in GP and SCL solns

47
Q

Polyquad is found in: (3)

A
  1. Unique pH
  2. Opti-Free products for SCLs
  3. Most Alcon preserved ATs
48
Q

Benzyl Alcohol

A

Good disinfection capabilities; negligible binding to GP lens surface

49
Q

What is benzyl alcohol effective with?

A

Lipid Removal

50
Q

Example of Benzyl alcohol?

A

Optimum CDS Solution

51
Q

CL Solutions (Products)

A

Next cards

52
Q

B&L Boston Line

A

Original, Advance, Simplus

53
Q

B&L Boston Line Condition Solution

A

-Disinfects and cushions
-Wetting agent that coats surface of lenses to make lenses smooth, wet, and comfortable
-Helps reduce friction between lens and eye

54
Q

Boston Original preservative? Viscosity?

A

Chlorhexidine; very thick viscosity

55
Q

Boston Advance / Simplus preservative(s) and viscosity?

A

Chlorhexidine (less than Original) and PAPB/Dymed; viscosity is less thick than Original

56
Q

Alcon Clear Care (Hydrogen Peroxide)

A

FDA approved use with GPS; NON-preserved

57
Q

Rub for Clear Care vs Clear Care Plus?

A

Required for Clear Care (GPs) but no rub required for Plus (just 5 sec rinse)

58
Q

Clear Care cannot be directly…..?

A

Cannot be placed into eye directly from bottle or before neutralization (wash hands after rubbing)

59
Q

Menicon Unique pH

A

Thin in bottle, thickens on eye due to ocular pH (enhance wettability)

60
Q

What preservative in Menicon Unique pH?

A

Polyquad; Also has H-Guar gelling agent (found in Systane also)

61
Q

Is Menicon Unique pH okay for Hydra-PEG?

A

Yes

62
Q

Tangible Clean

A

Multipurpose solution designed for use with Tangible Hydra-PEG coated lenses

63
Q

Tangible Clean can be used for?

A

Corneal GPs, Scleral, Hybrid, SCLs???

Contact Lens 1 (3 decks)

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