Classic Labs Flashcards

1
Q

↑AFP in amniotic fluid

A

Neural tube defect w/ ↑AChE

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2
Q

Anti-centromere Abs

A

Scleroderma limited = CREST

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3
Q

Anti-AMA Abs

A

1ary biliary cirrhosis - (female, cholestasis, portal HTN)

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4
Q

3 types of SLE Abs

A

ANA - sensitive
Anti-Smith, anti-dsDNA = specific
T3 HST

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5
Q

Anti-topoisomerase Abs

A

Diffuse scleroderma

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6
Q

Anti-platelet Abs

A

Idiopathic thrombocytopenic purpura

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7
Q

Anti-TG/gliadin/endomysial Abs

A

Celiac

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8
Q

Apple core lesion on barium enema XRay

A

L sided CRC

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9
Q

Azurophilic peroxidase + granular inclusions in granulocytes + myeloblasts

A

Auer rods - AML

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10
Q

Basophilic nuclear remnants in RBCs

A

Howell Jolly bodies - splenectomy

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11
Q

Yellow or bloody tap on lumbar puncture

A

Subarachnoid hemm

Yellow = xanthochromia

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12
Q

Brown tumor of bone

A

HyperPT or oseitis fibrosa cystica (deposited hemosiderin from hemm gives brown color)

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13
Q

Circular grouping of dark tumor cells surrounding pale neurofibrils

A

Homer Wright rosettes - neuroblastoma or medulloblastoma

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14
Q

Delta wave on EKG w/ supravent tachy

A

WPW syndrome - bundle of Kent bypasses AV node

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15
Q

Desquamated epithelium casts in sputum

Hexagonal, double pointed, needle like crystals in bronchial secretions

A

Bronchial asthma

  1. Crushmann spirals
  2. Charcot Leyden crystals
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16
Q

Disarrayed granolas cells arranged around collections of eosinophilic fluid

A

Call Exner bodies - granulosa cell tumor ovaries

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17
Q

Enlarged cell with intranuclear inclusion bodies

A

Owl eye CMV

18
Q

Enlarged thyroid cells with ground glass nuclei with central clearing

A

Orphan Annie eyes - pap carcinoma thyroid

19
Q

Eos cytoplasmic inclusion in liver cell

Vs eos globule in liver

A

Mallory body - alc liver disease

Vs hepatocyte undergoing apoptosis -> viral hep, yellow fever

20
Q

Eos cytoplasmic inclusion in neuron

Vs eos inclusion bodies in cytoplasm of hippocampal + cerebellar neurons

A

Lewy body - Park + Lewy body dementia

Vs Negri bodies of rabies

21
Q

Glomeruloid structure surrounding vessel in germ cells

A

Schiller Duval bodies - yolk sac tumor

22
Q

Crew cut skull xray

A

B thal or sickle cell

23
Q

Granulomatous heart nodules

A

Aschoff bodies of RHD

24
Q

High D dimers - 3 scenarios

A

DVT
PE
DIC

25
Q

Hypercoag leading to migrating DVTs and vasculitis

A

Trousseau syndrome - adenocarcinoma of the pancreas or lung

26
Q

Intranuc eos droplet like bodies

A

Cowdry type A bodies - HSV or VZV

27
Q

Iron containing nodules in alveolar sputum

A

Asbestosis

28
Q

Large granules in phagocytes in setting of immunodef

A

Chediak Higashi

29
Q

Lead pipe colon on imaging

A

UC (no haustra)

30
Q

Lytic punched out bone lesions on XR

A

Multiple myeloma

31
Q

Blue domed breast cyst

A

Fibrocystic change of breast

32
Q

4 reasons for monoclonal Ab spike

A
  1. Multiple myeloma - IgG or A
  2. MGUS
  3. Waldernstrom - IgM
  4. 1ary amyloidosis
33
Q

Nutmeg liver

A

Chronic liver cong due to RH fail

Or Budd Chiari

34
Q

Onion skin periosteal rxn

A

Ewing sarcoma (small blue cell tumor)

35
Q

Rectangular, crystal like, cytoplasmic inclusions in Leydig cells

A

Reinke crystals (Leydig cell tumor)

36
Q

Recurrent infections
Eczema
TCP

A

Wiskott Aldrich

37
Q

AIDs pt with ring enhancing lesion - single vs multiple

A

Single - CNS lymphoma

Multiple - toxo

38
Q

Stippled vaginal epi cells

A

Clue cells - Gardnerella

39
Q

Thumb sign on lateral neck XR

A

Epiglottitis H.influ

40
Q

Thyroid like appearance of kidney

A

Chronic pyelo

41
Q

WBC that are smudged

A

CLL