Clinical: Cerebellar disease

Question 1

Symptoms and Signs

Answer 1

Truncal and Gait ataxia Limb Ataxia Dysarthria Abnormal eye movements Vertigo Nausea/Vomiting

Question 2

Truncal/Gait ataxia

Answer 2

Unsteady without support; stands/walks with broad base; if lesion is on vermis of cerebellum trunk ataxia

Question 3

Limb Ataxia

Answer 3

Clumsiness/difficulty writing; intention tremor!; ataxia on ipsilateral side; impaired rapid alternating movements

Question 4

Dysarthria

Answer 4

Slurred speech, Staccato; sometimes dysphagia

Question 5

Abnormal eye movements

Answer 5

Nystagmus, often associated with oscillopsia (enviornment moving); diplopia (seeing 2)

Question 6

Tone power and tendon reflexes

Answer 6

T: normal or reduced P: normal TR: normal

Question 7

Causes of disease: Congenital; Inherited, degnerative; Imflammation; tumours; vascular disease; infections; metabolic

Answer 7

Congenital: Arnold Chiari (small skull) Inherited/ND: Spinocerebellar ataxia Inflammation: MS Vascular: Stroke Infections: abcesses and CJD (prions) Metabolic: alcohol

Question 8

Spinocerebellar Ataxia

Answer 8

Is an expansion of CAG triplet