Clinical Features AKI

Question 1

AKI Criteria

Answer 1

INC SCr by 50 within 7 days OR INC in SCr by 0.3 withing 2 days OR Oliguria

Question 2

Prerenal AKI Eti

Answer 2

• Vascular (RAS, HTN, vasculitis)
• Volume depletion (dehydration, diarrhea)
• Reduced effective volume (CHF, sepsis, burns)
• Meds (NSAIDS, ARBs/ACEi)

Question 3

ATN Eti

Answer 3

• Ischemic: sepsis, hemorrhage, Prerenal
• Nephrotoxic: NSAIDs, ACEi/ARBs, Radiocontrast, aminoglycosides, amphotericin B, Chemotherapeutics
• Endogenous: Myto/hermoglobin Myelomal URic Acid

Question 4

BUN/Cr RAtio and AKI

Answer 4

> 20/1 -> Prerenal

<20/1 -> Renal

Question 5

What does Rate of the rise in AKI>0.3mg/kg/d OR

>2mg%/day indicate?

Answer 5

Muscle breakdown

Question 6

Urinary Sodium + FeNa + AKI

Answer 6

< 10-20 mEq/L -> Prerenal
> 20-40 mEq/L -> Renal

<1% -> Prerenal
>3% -> Renal

Question 7

Urinalysis + AKI

Answer 7

Prerenal -> Bland sediment

ATN -> RTEs; Granular casts

Question 8

Management if ATN

Answer 8

• Prevention
• Volume expansion
• Loop Diuretics
• Low dose Dopamine

Question 9

Indications for dialysis

Answer 9

Acidosis
Electrolyte imbalance
Intoxication
Overload
Uremia