Clinical Features and Management of Restrictive Lung Disease Flashcards

1
Q

What is the physiological definition of restrictive lung disease?

A

FVC < 80% of best

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are lung causes of restrictive lung disease?

A

Sarcoidosis
Idiopathic pulmonary fibrosis
Hypersensitivity pneumonitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are pleural causes of restrictive lung disease?

A

Pleural effusions
Pneumothorax
Pleural thickening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How can a pleural effusion be a restrictive lung disease?

A

The fluid on the outside of the lung can compress the lung

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How can a pneumothorax be a restrictive lung disease?

A

The air in the pleural space can compress the lung or just cause it to collapse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most common cause of pleural thickening?

A

Asbestos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are some skeletal causes of restrictive lung disease?

A

Kyphoscoliosis
Ankylosing spondylitis
Thoracoplasty
Rib fractures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How can kyphoscoliosis cause restrictive lung disease?

A

It decreases chest expansion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How can ankylosing spondylitis cause restrictive lung disease?

A

It decreases chest expansion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How can thoracoplasty be a restrictive?

A

It prevents one lung from inflating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is a muscle cause of restrictive lung disease?

A

Amyotrophic lateral sclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are some sub-diaphragmatic of restrictive lung disease?

A

Obesity

Pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Where is the interstitium?

A

Between the epithelium of the alveolus and endothelium of the capillary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is sarcoidosis?

A

Multisystem granulomatous disease of unknown cause

Contains non-caveating granuloma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the investigation for sarcoidosis?

A
CXR 
PFT
FBC 
U+Es
urinalysis 
ECG 
TB skin test 
Eye exam 

Bronchoscopy: trans bronchial biopsies and endobronchial ultrasound
Mediastinoscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How is sarcoidosis treated if it is mild, no vital organ involvement, normal lung function and few symptoms?

A

No treatment

17
Q

Can sarcoidosis resolve itself?

A

Yes

18
Q

What is the treatment of sarcoidosis with erythema nodosum?

A

NSAIDs

19
Q

What is the treatment of sarcoidosis, anterior uveitis, cough and skin lesions?

A

Topical steroids

20
Q

What is the treatment for cardiac, neurological, eye disease (not responding to topical steroids) and hypercalcaemia?

A

Systemic steroids

21
Q

What are complications of sarcoidosis?

A

Progressive respiratory failure
Bronchiectasis
Aspergilloma, haemoptysis, pneumothorax

22
Q

What does idiopathic pulmonary fibrosis typically present with?

A
Chronic SOB and cough 
Older men 
No response to treatment for LVF or infection 
Clubbing 
Crackles
23
Q

What is the management for idiopathic pulmonary fibrosis?

A

Refer to Interstitial lung disease clinic
Oral anti-fibrotic - pirfenidone, nintedanib
Palliative care
Transplant