çocuk sağlığı ve hastalıkları

Question 1

By ….., gonadal sex is determined

Answer 1

6 weeks

Question 2

…….. weeks development of internal and external genitalia= sexual differentiation

Answer 2

6-12 weeks

Question 3

Testosterone

Answer 3

Wolffian ducts oluşumu

Question 4

AMH

Answer 4

Mullerian

Question 5

Testosterone must be converted into

Answer 5

Dihydrotestosterone (DHT)

Question 6

Testosterone- to - DHT

Answer 6

5a reductase sorumlu bu dönüşümden

Question 7

Estradiol produced by …… of Testosterone

Answer 7

Aromatization

Question 8

The most common cause of virilized females

Answer 8

Congenital adrenal hyperplasia

Question 9

11 B OHase deficiency

Answer 9

Second most common cause of CAH
Hypertension

Question 10

POR (cytochrome P450 oxidoreductase) deficiency

Answer 10

Antley- Bixler syndrome

Question 11

Clinival findings in congenital adrenal hyperplasia

Answer 11

Ambiguous genitalia
Hypertension- 11B and 17a hydroxylase deficiency

Question 12

46XY DSD with CAH

Answer 12

Defects of Testosterone synthesis with cortisol deficiency

Question 13

46 XY DSD without adrenal insufficiency

Answer 13

17/20 lyase deficiency
17 B hydroxysteroid dehydrogenase 3 deficiency
No mullerian structures
Normal cortisol levels

Question 14

Redistrubition of K by an increase in intracellular uptake

Answer 14

• alkalosis
• insulin
• medications