Conditions + Investigations

Question 1

Cushing’s

Answer 1

24hr Urine free Cortisol
Dexamethasone suppression test
Pituitary MRI

Question 2

Addison’s

Answer 2

Synacthen test

Random Cortisol
ACTH levels in plasma
Adrenal antibodies

Question 3

Conn’s

Answer 3

Aldosterone / Renin ratio

24hr Urine Aldosterone

Question 4

Pheochromocytoma

Answer 4

24hr Urine metanephrines

Question 5

DM

Answer 5

Random venous BG >11
OGTT >11 after 2hrs
HbA1c (type 2) >48

Question 6

Acromegaly

Answer 6

OGTT
IGF-1 in plasma
Pituitary MRI

Question 7

Diabetes Insipidus

Answer 7

Water deprivation

Question 8

Goitre

Answer 8

FNA, US of neck

Question 9

Hypocalcaemia

Answer 9

Bloods - Ca, Phosphate, PTH, Vit D

Question 10

Hypercalcaemia

Answer 10

Bloods - Ca, Phosphate, Vit D, PTH

U+Es - creatinine = renal failure?? (+Ca)

Question 11

Hyperthyroidism

Answer 11

TFT - fT4 + TSH

TSH receptor antibodies

Question 12

Hypothyroidism

Answer 12

TFT - fT4 + TSH

TPO + thyroglobulin antibodies

Question 13

Primary Hyperparathyroidism

Answer 13

Bloods - Ca, Vit D, PTH, Phospahate
24hr Urine Ca - checks it's not FHH (will be low in FHH but high in 1 Hyperpara)
DEXA scan - osteoporosis
Abdominal xray / CT - Kidney stones
US parathyroid glands

BONES, STONES, GROANS + PSYCHIC MOANS