COTE Flashcards

1
Q

Causes of Delirium (DELIRIUM acronym)
OR
(PINCH ME)

A

Drug use Electrolyte/physiological abnormality Lack of drug (withdrawal) Infection Reduced sensory input (blind/deaf) Intracrainial (stroke/meningitis) Urinary retention + faecal impaction Myocardial (MI/arrhythmia)

Pain, Infection, Nutrition, Constipation, Hydration, Medicines, Environment

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2
Q

Metabolic disturbances as a result of reinstitution of nutrition to patients who are starved/severely malnourished is called?

A

Refeeding Syndrome

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3
Q

Name an electrolyte/biochemical feature of Refeeding Syndrome

A

Hypophosphataemia, Hypokalaemia, Thiamine deficiency, Abnormal glucose metabolism

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4
Q

Name 3 risk factors for Osteoporosis

A

smoking early menopause, steroid use, underweight, inactivity, alcohol, age

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5
Q

How do Bisphosphonates work?

A

They inhibit the action of osteoclasts

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6
Q

Progressive neurological disorder impacting condition, which causes functional impairment

A

Dementia

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7
Q

a loss of resilience that means people do not bounce back quickly after a physical or mental illness, an accident or other stressful event

A

Frailty

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8
Q

Match the definition to the type of urinary incontinence:
a.) unable to reach the toilet in time, for such reasons as poor mobility or unfamiliar surroundings
b.) involuntary leakage of urine on effort or exertion, or on sneezing or coughing due to incompetent sphincter
c.) involuntary urine leakage accompanied by, or immediately preceded by, urgency of micturition
d.) involuntary leakage of urine associated with both urgency and exertion, effort, sneezing or coughing
e.) urgency that occurs with or without urge incontinence and usually with frequency and nocturia
f.) usually due to chronic bladder outflow obstruction. It is often due to prostatic disease in men
g.) may be due to a fistulous track between the vagina and the ureter, or bladder, or urethra. There is continuous leakage of urine

1.) Urge incontinence
2.) Mixed incontinence
3.) Overactive Bladder syndrome
4.) True incontinence
5.) Overflow incontinence
6.) Functional Incontinence
7.) Stress incontinence

A

a.) 6 b.) 7 c.) 1 d.) 2 e.) 3 f.) 5 g.) 4

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9
Q

a progressive systemic skeletal disease characterised by reduced bone mass and micro-architectural deterioration of bone tissue

A

Osteoporosis

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10
Q

Low bone mass (hip BMD between 1 and 2.5 SD below the young adult reference mean) is classified as?

A

Osteopenia

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11
Q

Low bone mass (hip BMD 2.5 SD or more below the young adult reference mean) is classified as?

A

Osteoporosis

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12
Q

What is the most commonly used bone density scan?

A

DEXA scan (dual-energy X-ray absorptiometry)

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13
Q

What is the WHO fracture risk calculator called and what does it calculate?

A

FRAX calculates ten-year probability of a major osteoporotic fracture in people aged 40-90

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14
Q

What is first line pharmacological management in postmenopausal women who have never had an osteoporotic fragility fracture (primary prevention)?

A

Bisphosphonate (Alendronate)

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15
Q

Name a monoclonal antibody that reduces osteoclast activity and a selective oestrogen receptor modulator (SERM) (both secondary prevention of osteoporotic fracture)

A

Denosumab and Raloxifene

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16
Q

How do bisphosphonates work?

A

Bisphosphonates bind to bone mineral and inhibit osteoclastic bone resorption

17
Q

3 main symptoms of Parkinson’s disease?

A

Resting tremor, Cogwheel Rigidity, Bradykinesia

18
Q

most common and 2nd most common neurodegenerative disorders

A

Alzheimer’s and Parkinson’s

19
Q

Alzheimer’s
Non-pharmacological management

A

Group cognitive stimulation therapy
Group reminiscence therapy

20
Q

Dementia vs delirium

A

Dementia
- Slow and progressive
- Alert
- Thought poverty
- Non-reversible

Delirium
- Rapid
- Fluctuating
- Clouded consciousness
- Hallucinations
- Reversible

21
Q

What is first-line for Delirium? (+ what would you give if patient has Parkinson’s?)

A

Lorazepam; Haloperidol

22
Q

Which 4 blood tests commonly included in confusion screen?

A
  • B12/folate: macrocytic anaemias, B12/folate deficiency worsen confusion
  • TFTs: confusion is more commonly seen in hypothyroidism
  • Glucose: hypoglycaemia can commonly cause confusion
  • Bone Profile (Calcium): hypercalcaemia can cause confusion
23
Q

Which screening tool used for risk of pressure sore?

A

Waterlow score

24
Q

Which type of dementia causes hallucinations?

A

Lewy body

25
Q

Features of Pick’s disease

A
  • personality change and impaired social conduct.
  • Other common features include hyperorality, disinhibition, increased appetite, and perseveration behaviours.
26
Q

What type of dementia is Pick’s disease

A

Frontotemporal

27
Q

Name an anticholinesterase

A

donepezil, galantamine, and rivastigmine

28
Q

What drug class is Memantine?

A

NMDA receptor antagonist

29
Q

What drug class is donepezil?

A

Acetylcholinesterase inhibitor