Cytogenetics II L10

Question 1

Define Metacentric

Answer 1

When centromere is right in the middle of p and q relativley equal in length

Question 2

Define submetacentric

Answer 2

When centromere is higher up therefore q is longer

Question 3

Define acrocentric

Answer 3

When centromere is high up and p is almost non-existent (but still there)

Question 4

Define translocation

Answer 4

Exchange of material between 2+ chromosomes

Question 5

What are the two types of translocations and define them

Answer 5

1. Balanced (reciprocal): identified by chance

2. Unbalanced: have a combination of monosome and trisome (picked up early)

Question 6

What is a Robertsonian translocation?

Answer 6

Occurs between acrocentric chromosomes

A loss of the non-critical genes in the short arm (p) regions