Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Histology > Cytoskeleton > Flashcards

Cytoskeleton Flashcards

1
Q

what two forms can actin be found in

A 
G actin (monomer)
F actin (polymer- double helix)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

atp bound actin is associated with which end of the growing polymer

A

plus/ barbed end

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

adp-bound actin is associated with which end of the actin polymer

A

the pointed/ minus end

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

the dynamic equilibrium of actin polymerization and depolymerization is known as what

A

treadmilling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

spectrin is…

A

actin binding protein

in RBCs, bind cytoskeleton to plasma membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

dystrophin

A

actin binding protein

bind cytoskeleton to plasma membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

villin/ fimbrin

A

actin binding protein

forms cross links in microvilli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

calmodulin/ myosin

A

actin binding protein

cross link actin in plasma membrane of microvilli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

alpha actinin

A

actin binding protein

cross links stress fiber, connects actin to membrane protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

filamin

A

actin binding protein

crosslink actin at wide angles to form gels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

thymosin

A

actin binding protein

prevents G actin from polymerizing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Profilin

A

actin binding protein

binds actin, facilitate exchange of ADP for ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

gelsolin

A

actin binding protein

caps actin filaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

cofilin

A

actin binding protein

triggers depolymerization at minus end

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

arp 2/3

A

actin binding protein

initiates growth of f actin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

phallodin

A

actin binding protein

binds actin and prevents depolymerization

17
Q

latrunculins

A

binds g actin inducing depolymerization

18
Q

two types of macula adherins where you can find intermediate filaments

A

desmosomes and hemidesmosomes

19
Q

an intermediate filament consists of a bundle of how many protofilaments

A

8

20
Q

type I intermediate filaments

A

acidic keratin

21
Q

type II intermediate filaments

A

neutral and basic keratins

22
Q

type III intermediate filaments

A

vimenton, desmin, periferin

23
Q

type IV intermediate filaments

A

neurofilament

24
Q

type V intermediate filaments

A

nuclear lamins

25
Q

type VI intermediate filaments

A

nestin

26
Q

how many protofilaments come together to form a microtubule

A

13

27
Q

what condition allows for fast growing microtubules at the plus end?

A

low calcium concentration

28
Q

*****agents that inhibit microtubule formation

A

colchicine
colcemid
vincristine
vinblastin (hodgekin lymphoma)

29
Q

***agent that stabalizes microtubule formation, inhibits depolymerization

A

taxol - used in breast cancer

30
Q

cytoskeleton is made of what 3 components

A

microfilament (actin)
intermediate filament
microtubule

31
Q

what are the functions of the cytoskeleton

A 
cell movement
support/ strength
phagocytosis
mitotic spindle formation
cytokinesis
cell adherence
change in cell shape

Histology (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions