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APEA > Diabetes Meds > Flashcards

Diabetes Meds Flashcards

1
Q

What should you not give the TZDs with (which disease)?

A

Heart failure

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2
Q

How often do you test for DM?

A

Annually for BMI 25 and one other risk factor

Entire population greater than 45 every three years if normal

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3
Q

What medications are SGLT2 inhibitors?

A

-gliflozin- invokana

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4
Q

What do thiazolidinediones do?

A

Preserves beta cell function, improves insulin response of cells

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5
Q

What’s the MOA of GLP-1 Agonists?

A

glucagon like peptide, increases production of insulin in response to elevated BG level

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6
Q

Goals for DM?

A

Most adults <7
Older <8
Type 1 and pregnant <6

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7
Q

What medications are in sulfonulurieas?

A

Glimepiride, glipizide, glyburide

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8
Q

What do DDP-4 agents do?

A

Increases release of uncertain, and decreases release of glucagon

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9
Q

What medications are GLP-1 Agonists?

A

-TIDEs, victoza

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10
Q

What medical condition is associated with the use of exantide (DLP 1 agonist)?

A

Pancreatitis

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11
Q

How much do DPP-4 reduce A1C?

A

.7%

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12
Q

What is pioglitazone associated with?

A

Bladder cancer

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13
Q

What medication is a biguanide?

A

metformin

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14
Q

How much to sulfonylureas reduce A1C?

A

1-2%

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15
Q

How much do the thiazolidinediones reduce A1C?

A

.7%

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16
Q

What do the SGLT2 inhibitors do?

A

prevent reabsorption of renal glucose, increases glucose excretion

17
Q

What are thiazolidinediones contraindicated in?

A

heart failure

18
Q

What medication is a DPP-4 inhibitor?

A

Gliptins (Januvia)

19
Q

What medications are TZDs?

A

-glitazones, rosiglitazone

20
Q

What is the MOA of sulfonylurea?

A

potentiate insulin secretion

21
Q

What disease is GLP-1 contraindicated in?

A

gastroparesis

22
Q

How much do GLP-1 Agonists reduce A1C?

A

1-1.5%

23
Q

What else is a good benefit for GLP-1 Agonists?

A

Weight loss of 2-6 pounds in a year

24
Q

What medications are in the DPP-4 category?

A

Gliptins

25
Q

BMI cut off for adults with one or more risk factors for DM?

A

25

26
Q

What are high doses of thiazolidinediones associated with?

A

Bone fractures, osteopenia

APEA (1 decks)

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