Digestion and absorption Flashcards

1
Q

Ingested food turned into smaller solubles through

A

Hydrolysis

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2
Q

Microvilli located in

A

Enterocytes

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3
Q

Where will the digestion of proteins, lipids and carbohydrates take place

A

In microvilli of enterocytes

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4
Q

Enzyme producing the first digestion of carbohydrates

A

Amylase

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5
Q

% of carbohydrates digested until the deglutition reaches the stomach

A

20-40%

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6
Q

Phase at which the carbohydrates are when deglutition reaches the duodenum

A

Pancreatic secretion phase

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7
Q

% of carbohydrate ingestion at pancreatic secretion phase

A

50-80%

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8
Q

After digestion in duodenum carbohydrates –> ?

A

Dextrins and disaccharides

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9
Q

Enzymes breaking down dextrins and disaccharides

A

Maltase, dextrinase, sacarase, lactase

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10
Q

After maltase, dextrinase, lactase, sacarase.. carbohydrates –> ??

A

Monosaccharides

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11
Q

Cotransporters in absorption of carbohydrates

A

SGLT1

GLUT2/5

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12
Q

SGTL1 is dependent on

A

Na+

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13
Q

SGLT1 transports

A

Glucose or galactose along with Na+

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14
Q

GLUT5 transports

A

Fructose

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15
Q

Why is not fructose transported with SGLT1

A

Because it does not need Na+

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16
Q

GLUT2 transports … to …

A

Galactose, glucose and fructose into capillaries

17
Q

Enzymes involved in digestion of proteins

A

Pepsin

Pancreatic enzymes

18
Q

% of pepsin in stomach

A

20%

19
Q

% of pancreatic enzymes in stomach

A

80%

20
Q

Trypsin, chymotrypsin, elastase, carboxypeptidase are

A

Pancreatic enzymes

21
Q

Digestion of proteins begins due to

A

Pepsin but main digestion is done through pancreatic enzymes

22
Q

Enzyme of chief cells

A

Pepsin

23
Q

What activated pepsin enzyme in chief cells

A

HCl (low pH)

24
Q

Endopeptides in protein digestion

A

Trypsin
Chymotrypsin
Elastase

25
Q

Exopeptides in protein digestion

A

Carboxypeptidases

26
Q

Function of endopeptidases

A

Break peptide bonds to create smaller polypeptides

27
Q

Function of exopeptidases

A

Act on extremes of Aa to liberate lose Aa one by one

28
Q

Lipophilic vitamins in lipid digestion

A

Vitamin A D E K

29
Q

Main enzymes in lipid digestion

A

Lingual lipase and pancreatic lipase

30
Q

Enzyme functioning at mouth for lipid digestion

A

Lingual lipase

31
Q

% of action of lingual lipase

A

10%

32
Q

Once digested lipids are transported to

A

Etythrocytes

33
Q

How do lipids reach the erythrocyte

A

Through emulsion and solubilization of fats through biliary salts

34
Q

Emulsionated fat –> free fatty acids and monoglycerides through

A

Pancreatic lipase

35
Q

Action of pancreatic lipase not efficient if

A

Fat droplets have not been emulsified by bile salts

36
Q

After lipase action the lipid droplets are called

A

Micelles

37
Q

Absorption of short chain fatty acids in

A

Enterocytes

38
Q

Rest of lipids are packed into

A

Chylomicrons through apo-lipoproteins

39
Q

What makes the lipids into chylomicrons

A

Apo-lipoproteins