Diuretics - Thiazide Flashcards

1
Q

Which part of the nephron does Thiazide and Thiazide like Diuretics work on ?

A

Inhibit the NA+/CL- cotransporter in the distal convoluted tubule of the nephron.

Preventing absoprtion of water and its osmotically associated water.

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2
Q

What is the differene between Thizide and Thiazide like Diuretics ?

A

Both work in the same way

Thiazides are benzothiadazine derivatives.

Thiazide-Like Diuretics are Sulfonadime derivates.

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3
Q

When are thiazides indicated ?

A

Hypertension

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4
Q

Why can Thizide diuretics precipitate acute attacks of gout ?

A

They reduce uric acid excretion.

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5
Q

What is gout ?

A

Gout is a type of arthritis that causes sudden, severe joint pain. Painkillers can help the pain and healthier lifestyle choices can prevent future attacks.

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