DNA Damage

Question 1

For base excision repair, what is used to remove a base?

Answer 1

DNA glycosylase

Question 2

For base excision repair, what is used to remove backbone that is connected to the base?

Answer 2

AP Endonuclease

Phosphodiesterase

Question 3

What adds a new proper base s/p base excision repair?

Also true for nucleotides in nucleotide excision repair

Answer 3

DNA Polymerase

DNA Ligase

Question 4

For nucleotide excision repair, nucleotide can be nicked by?

Answer 4

Excision Nuclease

Question 5

What enzymes removes the nucleotide?

Answer 5

DNA Helicase

Question 6

What is a holiday junction?

Answer 6

4 Strands from two different helices

Question 7

DNA Only Transposon requires what enzymes

Answer 7

Transposase

Question 8

Retroviral-like retrotransposons requires what enzymes

Answer 8

Reverse transcriptase and integrase

Question 9

Nonretroviral retrotranposons require what enzymes

Answer 9

Reverse transcriptase and endonuclease

Question 10

DNA Only Transposon move by?

Answer 10

Moves as DNA, either by cut and paste or replicative pathways

Question 11

Retroviral-like retrotransposons

Answer 11

Moves via RNA intermediate whose production is driven by promoter in the LTR

Question 12

Nonretroviral retrotranposons

Answer 12

Moves via RNA intermediate that is often synthesized from neighboring promoter