Dna, Rna and protein synthesis unit #1 Flashcards

1
Q

What does DNA stand for

A

DNA stands for deoxyribonucleic (dee-OK-see-ri-bo-new-klee-ik) acid. It is the genetic information inside the cells of the body that helps make people who they are.

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2
Q

Two reasons why DNA is unique

A

-To store and use info to direct activities of cells
- to copy itself exactly

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3
Q

building blocks of DNA (monomers)

A

nucleotides

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4
Q

3 parts of a nucleotide?

A

1, deoxyribose
2. phosphate
3. nitrogen base

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5
Q

what are the 4 nitrogen bases in DNA?

A

Adenine + Guanine
Thymine + Cytosine

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6
Q

What are pyrimidines? How many rings do they have?

A

Thymine + Cytosine, Single ringed structures

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7
Q

what are Urines? how many rings do they have?

A

Adenine + Guanine, double-ringed structures

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8
Q

the double helix structure of DNA was descovered by 4 scientists - what are their names and whawas the year?

A
  • Erwin Chargaff 1949
  • Rosalina Franklin 1953
  • Watson 1953
  • Crick 1953
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9
Q

What did Erwin Chargaff discover?

A

Erwin Chargaff found that in DNA, the ratios of adenine (A) to thymine (T) and guanine (G) to cytosine (C) are equal.

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10
Q

What enzyme unzips the 2 strands of DNA in DNA replication?

A

DNA Helicase

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11
Q

DNA polymerase what does it do?

A

Hydrogen bonds link those complements to the “old” strand of DNA with the help of this enzyme

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12
Q

What is the “Backbone” of DNA made up of

A

Sugar?phosphate

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13
Q

What are the 3 types of RNA?

A
  • Messenger RNA (mRNA)
  • Transfer RNA (tRNA)
    -Ribosomal RNA (rRNA)
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14
Q

Messanger RNA function

A

Found in nucleus, then moves to cytoplasm through nuclear pores single, uncoiled chain: carries genetic info of DNA in the nucleus to the cytoplasm

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15
Q

Transfer RNA

A

Found in cytoplasm bonds to a specific amino acid and carries the amino acid to ribosomes

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16
Q

Ribosomal RNA

A

Found in ribosomes RNA functions in the ribosomes as a metabolic molecule that aids in protein sythesis

16
Q

Steps of Transcription?

A
  1. An enzyme called RNA polymerase binds to a specific region in DNA molecule called the promoter site. promoter sites have specific base sequences. promoters are signals in DNA that indicates to the enzyme where binds to RNA.
  2. seperation of complementery strands of DNA occurs
  3. RNA polymerase than uses one strand of DNA as a template from which nucleotides are assembled into a strand of RNA
  4. polymerase reaches the termination site, and the newly made Rna released
  5. The New RNA strand moves from the nucleus to the cytoplasm through the nucleus pores
17
Q

Transcription takes place in the…

A

Cytoplasm. it will be read by a ribosome to make a protein. protein synthesis is important because proteins play roles in enzymatic action, transport, motion, protection, support, communication and regulation.

18
Q

4 Differences between DNA and RNA

A

of strands present: DNA: 2, RNA: 1
Name of 5- carbon sugar: DNA: Deoxyribose, RNA: Ribose
Nitrogen bases: DNA: AT CG, RNA: AU CG
DNA long term, RNA is temporary

19
Q

what holds DnA molecules together?

A

Hydrogen Bonds

20
Q

Nitrogen bases are always connected to the?

A

Sugar molecule

21
Q

How does mRNA move from the nucleus to the cytoplasm of a cell?

A

through pores in the nuclear membrane.

22
Q

What are introns and exons

A
23
Q

What are the 3 nitrogen bases on mRNA called?

A

The bases in mRNA are grouped into sets of three called codons.

24
Q

what is the universal start codon

A

AUG, encodes the amino acid methionine

25
Q

3 stop codons

A

3 are stop codons (i.e., UAA, UAG and UGA

26
Q

Translation takes place in? what is it?

A

in Cytoplasm, proteins are produced using RNA molecules as templates. The generated protein is a sequence of amino acids.

27
Q

What is Mutation?

A

Any change in DNA sequence of a cell

28
Q

Mutations that produce changes in a single gene are called

A

point mutations

29
Q

Mutations that create changes in a whole chromosome are known as

A

chromosomal mutations

30
Q

In what ways do mutations change organisms

A

harm an organism’s ability to survive and reproduce.

31
Q

what are the 3 examples of gene (point) mutations

A

Base substitutions are point mutations where one base is swapped for another. Insertions are point mutations where one or a few bases are added at one location in a DNA sequence. Deletions are point mutations where one or a few bases are removed from one location of a DNA sequence.

32
Q

nsertion and deletions usally result in framshift mutations?

A

it alters the reading frame and completely changes the amino acid sequence

33
Q

4 examples of chromosomal mutation?

A

deletion, duplication, inversion, and translocation ( explain each)