Drug doses

Question 1

Flucloxacillin

Answer 1

500mg orally very 6 hrs for 10 days

Treats:
- Staph infections of the skin or pneumonia

Question 2

Amoxycillin

Answer 2

Oral - 500mg TDS
Otitis media - 15mg/kg up to 500mg, 8hrly for 5 days.
Mild CAP - 1000mg, 8hrly for 5-7days

Treats:
Moderate spectrum
-	Listeria
-	Gram negative cocci
-	Gram negative bacilli 
Eg. bacterial sinusistis, otitis media,

Question 3

Amoxycillin with Clavulanic acid

Answer 3

Penicillin & β-lactamase inhibitor

Oral
500mg/125mg bd for 5 days (cystitis)
875mg/125mg bd for 10 days (pyelonephritis)

Infections it’s used to treat:
Cystitis, pyelonephritis

Question 4

Cephalexin

Answer 4

Cephalosporin

Oral
1g bd for 10 days (skin) or
500mg bd for 10 days (UTIs)

Infections it’s used to treat:
Acute pyleonephritis, UTIs, skin infections (cystitis, folliculitis, impetigo, boils/carbuncles)

Question 5

Chloramphenicol (topically for bacterial conjunctivitis)

Answer 5

Other antibacterial

Topical
0.5% eye drops – 1-2 drops every 2h in the first 24h.  to 6 hrly as infection improves (up to 7 days)

1% ointment – used at bedtime

Bacterial Conjunctivitis

• haemophilus influenza
• staph aureus
• neisseria gonorrheae

Question 6

Clindamycin

Answer 6

Linclosamide

Oral
For patients with penicillin hypersensitivity:
450mg 8hrly for 5 days
450mg 8hrly for 7-10 days

Boils/Carbuncles
Cellulitis

Question 7

Co-trimoxazole

Bactrim®

Answer 7

Other antibacterial (combination)
Trimethoprim WITH sulfamethoxazole

Oral
160mg trimethoprim/ 800mg sulfamethoxazole bd for 5 days

For Listeria monocytogenes & immediate penicillin or cephalosporin hypersensitivity.
Melioidosis
shigellosis

Question 8

Doxycycline

Answer 8

Tetracycline
Generally used when penicillin hypersensitivity present.

Oral
100mg bd
	EO = 14 days
	Acute bacterial sinusitis = 5-7 days
	Moderate CAP = 7 days
200mg for 1st dose then 100mg bd for 5 days (mild CAP)

EO
Urethritis/cervictitis (clamydia and gonorrehae infections)
Acute bacterial sinusitis
Mild CAP
Moderate CAP
Legionella pneumonia (5-14days)
Mycoplasma paneumoia (up to 14 days)
Acne & Rosatia (50mg daily)
Prevention of Malaria (100mg daily)

Question 9

Famciclovir (oral for cold sores)

Answer 9

Guanine analogue

Oral
Herpes 1500mg as a single dose (HSV-1)

Take with glass of water (can upset stomach)

Question 10

Fluconazole (oral for vaginal thrush)

Answer 10

Azole (anti-fungal)

Oral
150mg single dose
Prophylaxisis – 150mg every 3 days for 3 doses, then once a week.

Vaginal thrush

Try Topical products first