Drug-Herb Interactions

Question 1

What drug class do NSAIDs tend to react with? What do they do?

Answer 1

NSAIDs can reduce the efficacy of anti-hypertensives

Question 2

What mineral deficiencies can results from diuretic use? What side-effects can these cause?

Answer 2

hypocalcemia
hypomagnesemia–> dysrhythmia
hypokalemia–> dysrhythmia
low Thiamine–> cardiac dysfunction

Question 3

How might B-blockers interact with Calcium?

Answer 3

Calcium can reduce blood levels of Atenolol by 50%!

Question 4

How might B-blockers affect potassium and CoQ10?

Answer 4

B-blockers can increase serum potassium

B-blockers can cause CoQ10 depletion

Question 5

What food interacts with Ca-Channel blockers? How?

Answer 5

Grapefruit juice potentiates Ca-channel blockers like felodipine

Question 6

Concurrent use of ACE inhibitors with _____ can lead to life threatening hyperkalemia

Answer 6

ACE inhibitors plus potassium sparing diuretics –> hyperkalemia

Question 7

How do ACE inhibitors affect potassium levels?

Answer 7

ACE-Inhibitors are potassium sparing

Question 8

How do ACE-Inhibitors and Iron interact?

Answer 8

they decrease absorptions of each other