Drug Quiz 9 Complete Flashcards

1
Q
penicillin V potassium
Brand?
TC?
MOA?
AE?
A

Brand: Veetids, Pen-Vee K, V-cillin
TC: antibiotic
MOA: inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
AE: hives, rash

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2
Q
amoxicillin
Brand?
TC?
MOA?
AE?
A

Brand: Amoxil, Moxatag, Trimox
TC: antibiotic
MOA: inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
AE: diarrhea, rash

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3
Q
amoxicillin with clavulanate
Brand?
TC?
MOA?
AE?
A

Brand: Augmentin (XR)
TC: antibiotic
MOA: amoxicillin - inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme; clavulanate - binds to active sites of beta-lactamase enzymes
AE: diarrhea, rash

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4
Q
azithromycin
Brand?
TC?
MOA?
AE?
A

Brand: Zithromax, Zmax
TC: antibiotic
MOA: binds to 50S ribosome and suppresses protein synthesis
AE: diarrhea

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5
Q
cefdinir
Brand?
TC?
MOA?
AE?
A

Brand: Omnicef
TC: cephalosporin antibiotic
MOA: inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
AE: diarrhea, vaginal moniliasis

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6
Q
cefprozil
Brand?
TC?
MOA?
AE?
A

Brand: Cefzil
TC: cephalosporin antibiotic
MOA: inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
AE: diarrhea, rash

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7
Q
cefuroxime axetil
Brand?
TC?
MOA?
AE?
A

Brand: Ceftin
TC: cephalosporin antibiotic
MOA: inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
AE: diarrhea, rash, hives, itching

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8
Q
cephalexin
Brand?
TC?
MOA?
AE?
A

Brand: Keflex
TC: cephalosporin antibiotic
MOA: inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
AE: diarrhea, rash, hives, itching

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9
Q
ciprofloxacin
Brand?
TC?
MOA?
AE?
A

Brand: Cipro (XR)
TC: fluoroquinolone antibiotic
MOA: inhibits synthesis of bacterial DNA by interfering with enzyme DNA gyrase
AE: diarrhea, sun sensitivity, rash

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10
Q
levofloxacin
Brand?
TC?
MOA?
AE?
A

Brand: Levaquin
TC: fluoroquinolone antibiotic
MOA: inhibits synthesis of bacterial DNA by interfering with enzyme DNA gyrase
AE: diarrhea, taste perversion, tendonitis, tendon rupture

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11
Q
ofloxacin ophthalmic
Brand?
TC?
MOA?
AE?
A

Brand: Ocuflox
TC: fluoroquinolone antibiotic
MOA: inhibits synthesis of bacterial DNA by interfering with enzyme DNA gyrase
AE: eye problems, blurry vision

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12
Q
clarithromycin
Brand?
TC?
MOA?
AE?
A

Brand: Biaxin (XL)
TC: antibiotic
MOA: binds to 50S ribosome and suppresses protein synthesis
AE: diarrhea

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13
Q
clindamycin (oral)
Brand?
TC?
MOA?
AE?
A

Brand: Cleocin
TC: antibiotic
MOA: binds to 50S ribosome and suppresses protein synthesis
AE: severe diarrhea, muscle pain, rash

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14
Q
doxycycline hyclate
Brand?
TC?
MOA?
AE?
A

Brand: Vibramycin
TC: antibiotic
MOA: blocks protein synthesis by competitively binding to 30S ribosome
AE: sunlight sensitivity, teeth discoloration, sore tongue

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15
Q
minocycline hydrochloride
Brand?
TC?
MOA?
AE?
A

Brand: Minocin
TC: antibiotic
MOA: blocks protein synthesis by competitively binding to 30S ribosome
AE: burning stomach, teeth discoloration, sore tongue

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16
Q
nitrofurantoin
Brand?
TC?
MOA?
AE?
A

Brand: Macrodantin, Macrobid
TC: antibacterial
MOA: inhibition of acetyl coenzyme A
AE: diarrhea, fever, chills

17
Q
sulfamethoxazole with trimethoprim
Brand?
TC?
MOA?
AE?
A

Brand: Bactrim, Septra
TC: antibiotic
MOA: trimethoprim - blocks tetrahydrofolic acid; sulfamethoxazole - inhibits dihydrofolic acid by competitive antagonism
AE: diarrhea, rash

18
Q
mupirocin (topical)
Brand?
TC?
MOA?
AE?
A

Brand: Bactroban
TC: antibiotic
MOA: inhibition of bacterial protein synthesis by reversibly binding to bacterial isoleucyl transfer-RNA synthetase
AE: burning, stinging, pain

19
Q
metronidazole
Brand?
TC?
MOA?
AE?
A

Brand: Flagyl
TC: antibacterial/antiprotozoal
MOA: bind to DNA causing DNA strand breakage and death
AE: seizures, neuropathy

20
Q
fluconazole
Brand?
TC?
MOA?
AE?
A

Brand: Diflucan
TC: antifungal
MOA: cytochrome P450 sterol inhibitor
AE: abdominal pain, diarrhea, taste perversion

21
Q
ketoconazole
Brand?
TC?
MOA?
AE?
A

Brand: Nizoral
TC: antifungal
MOA: impairs synthesis of ergosterol allowing increased permeability and leakage of cellular components
AE: N/V, severe irritation

22
Q
nystatin
Brand?
TC?
MOA?
AE?
A

Brand: Nystop
TC: anti fungal, topical
MOA: antimycotic, binding to sterols in cell membrane, changing membrane permeability
AE: topical AE - burning, itching, rash; oral AE - diarrhea, GI distress

23
Q
terbinafine
Brand?
TC?
MOA?
AE?
A

Brand: Lamisil
TC: antifungal
MOA: inhibits squalene epoxidase
AE: diarrhea, abdominal pain, dyspepsia

24
Q
oseltamivir phosphate
Brand?
TC?
MOA?
AE?
A

Brand: Tamiflu
TC: antiviral
MOA: inhibition of influenza virus neuraminidase and alteration of virus particle aggregation and release
AE: seizures, confusion, abnormal behavior

25
Q
valacyclovir
Brand?
TC?
MOA?
AE?
A

Brand: Valtrex
TC: antiviral
MOA: interferes with HSV DNA polymerase and inhibits viral DNA replication
AE: H/N/V, abdominal pain

26
Q
acyclovir
Brand?
TC?
MOA?
AE?
A

Brand: Zovirax
TC: antiviral
MOA: interferes with HSV DNA polymerase and inhibits viral DNA replication
AE: creatine elevations, rash, hives, topical issues

27
Q
emtricitabine, tenofovir disoproxil fumarate, cobicistat, and elvitegravir
Brand?
TC?
MOA?
AE?
A

Brand: Stribild
TC: antiviral
MOA: combination activity, interferes wit HIV-1 DNA/RT/integrase
AE: lactic acidosis, insomnia, abnormal dreams

28
Q
chlorhexidine gluconate
Brand?
TC?
MOA?
AE?
A

Brand: Peridex, Periogard
TC: anti plaque rinse
MOA: disruption of plasma membrane of bacterial cell
AE: alteration of tase, mouth irritation, staining

29
Q
trimethoprim sulfate and polymyxin B sulfate
Brand?
TC?
MOA?
AE?
A

Brand: Polytrim
TC: ophthalmic antibiotic
MOA: polymyxin B - interacts with bacterial cell membrane, disrupts permeability; trimethoprim - blocks production of tetrahydrofolic acid by inhibiting the enzyme dihydrofolate reductase
AE: burning, stinging, redness

30
Q
tobramycin with dexamethasone
Brand?
TC?
MOA?
AE?
A

Brand: TobraDex
TC: ophthalmic antibiotic and anti-inflammatory
MOA: tobramycin - inhibits bacterial protein synthesis; dexamethasone - forms steroid receptor complex
AE: itching, swelling, conjunctival erythema

31
Q
neomycin, polymyxin, hydrocortisone
Brand?
TC?
MOA?
AE?
A

Brand: Cortisporin Otic
TC: otic antibiotic/anti-inflammatory
MOA: hydrocortisone - stimulates transcription and synthesis of proteins; neomycin - inhibits bacterial protein synthesis by binding to 30S; polymyxin B - interacts with bacterial cell membrane disrupting permeability
AE: local irritation, itching, burning