Drugs Flashcards
What 5 drugs cover Anaerobes
Metronidazole, Clindamycin, Moxifloxacin, Augmentin, Zosyn
What drugs are given for “clean” surgeries?
None, Cefazolin IV (60 min prior to incision; <120kg get 2g, >120kg get 3 g), Clindamycin IV
What are 2 antiviral drugs
Acyclovir, famcyclovir, valacyclovir, etc
How many days before surgery do you have to stop NSAIDs and COX2 inhibitors?
3 days prior
What agent can you use to “bridge”
Low molecular heparin (much shorter half life than warfarin)
What Abx prophylaxis should you use for endocarditis ppl?
Cefazolin
What abx should be given for a GI procedure?
Cefoxitin or Cefoteten; Clindamycin + aminoglycoside; Cefazolin + metronidazole
Name 6 drugs that cover MRSA
Bactrim, Vancomycin IV, Clindamycin, Linezolid, Doxycycline, Bactroban
What drug should be given for a “dirty” surgery
Broad spectrum—> Zosyn (piperacillin/tazobactam), Meropenem, Invanz, Unasyn, Primaxin, Timentin
How many days prior to surgery do you need to stop Clopidogrel (Plavix)
5-7 days
Name 5 drugs that have Gram Negative coverage
Ciprofloxacin, Gentamycin, Tobramycin, Zosyn, Cefuroxime, Ceftriaxone, Ceftazidine, Cefepime, Meropenem, Imipenem
How many days prior to surgery must you stop Oral contraceptives and HRT for high risk VTE procedures?
4-6 weeks
Name 5 drugs that cover Pseudomonas (Gram negative rod)
Ciprofloxacin or Levofloxacin, Zosyn, Ceftazidine or Cefepime, Tobramycin, -penem class
What drugs should be given for a “clean contaminated” surgery
IV Cefazolin + metronidazole
What Abx prophylaxis should be used for abdominal surgical ppx?
Ampicillin/sulbactam; ceftriaxone + Metronidazole
How many days before surgery should you stop using ASA?
7-10 days
How many days before surgery should you stop using DOACs (Eliquis, Xarelto, Pradaxa)
2-3 days
Name 6 drugs with Gram positive coverage
Clindamycin, Vancomycin, Linezolid, Daptomycin, Penicillins, Cephalosporins, Augmentin (broad), Zosyn (broad)
How many days prior to surgery should you stop warfarin?
5 days
What are 4 notable side effects of Abx
Diarrhea, GI upset, Resistance, Hypersensitivity, Red Man Syndrome (Vanco)