Drugs

Question 1

Name two dopamine agonists

Answer 1

Ropinirole

Pramipexole

Question 2

Name two MAO-Bi

Answer 2

Rasageline

Seleginine

Question 3

Name a COMTi

Answer 3

Entacapone

Question 4

Which PD drug has the greatest adverse effects?

Answer 4

Dopamine agonists

Question 5

What is the main SE of dopamine agonists? Who should not be given them?

Answer 5

Promotes impulsive behaviour - not in alcoholics, gambling addicts.

Question 6

What are the main SEs of carbamazepine? (3)

Answer 6

Rash
N+V
SIADH

Question 7

What are the main SEs of sodium valproate? (5)

Answer 7

Sedation 
Tremor 
Increased appetite 
Liver failure 
Encephalopathy

Question 8

What are the main SEs of lamotrignine? (2)

Answer 8

Rash

Diplopia

Question 9

Name three cholinesterase inhibitors

Answer 9

Rivastigmine
Donepzil
Galantamine

Question 10

What is the mechanism of action of Triptans? In which condition are they mainly used?

Answer 10

5HT receptor agonists - migraines

Question 11

What is the mechanism of action of pyridostigmine?

Answer 11

Long acting anti-cholinesterase

Question 12

What is the mechanism of action of carbamazepine and phenytoin?

Answer 12

Increase the refractory period of Na+ channels

Question 13

Which drugs is Steven-Johnson syndrome associated with? (3)

Answer 13

Carbamazepine, lamotrigine, allopurinol