E01_10 Prescribing: Pregnancy

Question 1

2018_Pregnancy

Guidelines used in prescribing pharmaceutical drugs to pregnant women?

A. Old, more established drugs over newer drugs
B. Negative effects in animal studies are always present in humans in the therapeutic ratio
C.
D. AOTA

Answer 1

A. Old, more established drugs over newer drugs

Question 2

2016, 2017_Pregnancy

Drugs & FDA Category

Answer 2

A - Folic Acid
B - Metronidazole
C - Most of the drugs
D - Phenytoin
X - Thalidomide, ARB

Question 3

2016_Pregnancy

Heparin is the anti-coagulant of choice for pregnant patients because:

A. Heparin is a highly lipophilic drug
B. Heparin is very large and polar molecule and unable to cross placenta
C. Heparin has genetic binding to maternal plasma protein more than fetal plasma protein
D. Heparin has placental transport pumps back into maternal circulation

Answer 3

B. Heparin is very large and polar molecule and unable to cross placenta

Question 4

2016_Pregnancy

Principles of rational prescribing in pregnancy include which of the following:

A. Minimize fetal risk by giving lowest effective dose of the drug
B. Drugs that have teratogenic effects in animals will always present with risk of malformations in infants given at clinical doses
C. Trials of new drugs in pregnant women are avoided to minimize risk of fetal malformations
D. AOTA

Answer 4

D. AOTA

Question 5

2016, 2017_Pregnancy

Drug of choice for pregnant patient (26th week AOG) with UTI

A. Tetracycline
B. Penicillin
C. Quinolones
D. Any of the above

Answer 5

B. Penicillin

Question 6

2017_Pregnancy

Anti-HTN of choice for pregnant patients

A. Nifedipine
B. Methyldopa
C. Hydralazine

Answer 6

A or B

ESC: Methyldopa, Nifedipine and Labetalol as first line meds

Question 6

2017_Pregnancy

True statement on physiologic and related PK changes in pregnancy

Answer 6

Because of the 50% increase in plasma volume and body water, drug doses should be increased in pregnant patients taking water-soluble drugs