EC coupling

Question 1

What does ALS effect?

Answer 1

motor neuron death in spinal chord causes weakness, spasticity and muscle atrophy

Question 2

What do demyelinating disease such as guillan-barre cause?

Answer 2

Autoimmune against myelin causes ascending paralysis and weakness

Question 3

What does myasthenia Gravis Cause?

Answer 3

Autoimmune agains Ach receptors at neuromuscular junction causes muscle fatigue, weakness, and sometimes paralysis

Question 4

What does malignant hyperthermia cause?

Answer 4

Mutation in Ryanodine receptor causing excessive calcium release (can be triggered by inhaled anesthetics) blood CO2 buildup, hyperthermia, circulatory collapse.