Embryology Flashcards

1
Q

What is NTD

A

Neural tube defects

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2
Q

NTDs tha affect the brain are called

A

Anencephaly

Encephalocele

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3
Q

A NTD that affects the spinal cord is called

A

spina bifida

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4
Q

What is anencephaly

A

failure of the upper part of the neural tube to close all the way.
Forebrain and cerebrum might be missing.
Remaining parts of brain often uncovered.

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5
Q

What is encephhalocele

A
Failure of Neurulation.
Occurs early in pregnancy.
part of skull doe not close completely 
Causes part of brain to come through the open skull.
Can be located in:
Back of skull.> girls 
Front of skull.> boys 
Area of nose, sinuses and forehead
Top of skull.
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6
Q

What is the name for a bulge that includes a pouch of brain and meninges.

A

meningoencephalocele.

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7
Q

What is the name for a encephalocele that contains brain tissue as well as a ventricular cistern

A

meningohydroencephalocele

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8
Q

What are three types of Spina Bifida

A

Myelomeningocele: Sac of fluid w part of spinal cord and nerves, they are usually damaged.
Meningocele: Sac of fluid, usually little or no nerve damage.
Spina bifida occulta: Small gap in the spine, w/o opening or sac on the back.

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9
Q

What structures are in an arch

A
Nerve
Cartilage
Artery
Internal endodermal Pharyngeal pouch
External ectodermal pharyngeal cleft
Mesenchymal core of somatic mesoderm 
Neural crest mesenchyme
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10
Q

How many pharyngeal arches are there

A

five

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11
Q

How many pharyngeal pouches are there

A

four

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12
Q

What comes from the first pouch

A

pharyngotympanic tube

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13
Q

What comes from the second pouch

A

Tonsil

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14
Q

What comes from the third pouch

A

Thymus and inferior parathyroid

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15
Q

what comes from the fourth pouch

A

Superior parathyroid
Ultimobranchyal body
C-cells of the thyroid.

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16
Q

What forms the outer pharyngeal clefts (grooves)

A

Ectoderm

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17
Q

What forms from the cartilage of the first arch

A

Palatopterygoquadrate cartilage; maxilla and incus

Meckel’s cartilage; mandible and malleus

18
Q

What forms from the somatic mesoderm of the first arch

A

terminal branch of the maxillary artery.

Muscles of mastication: Masseter, temporalis and pterygoids.

19
Q

what forms from the cartilage of the second arch

A
Reichert's cartilage.
Stapes
Styloid process.
Styloid Hyoid ligament.
Lesser horns and upper rim of hyoid bone.
20
Q

What forms from the somatic mesoderm of the second arch

A

muscles of facial expression: orbicularis oculi, orbicularis oris, risorius, platysma, auricularis, fronto occypitalis, buccinator.
Posterior belly of digastric.
stylohioid

21
Q

What nerve innervates the second arch

A

facial nerve CN VII

22
Q

What nerve innervates the first arch

A

trigeminal nerve CN V

23
Q

if the lateral cervical sinus from the second arch persists what is the resuls

A

a cervical cyst anterior to the SCM muscle

24
Q

if a cervical cyst opens into the outside or the inside, it is via a

A

cervical fistula.

Internal fistula opens into the palatine tonsil.

25
Q

What forms from the cartilage of the third arch

A

Lower rim of hyoid bone. (body)

Greater horn of hyoid.

26
Q

What forms from the somatic mesoderm of the third arch

A

Stylopharyngeus muscle

27
Q

What two arteries are associated with the third arch

A

Common carotid artery

Internal carotid artery

28
Q

What nerve innervates the third arch

A

glossopharyngeal nerve CN IX

29
Q

What gives rise to the laryngeal cartilages

A

the lateral plate of the fourth and sixth arches

30
Q

What innervates the fourth arch

A

the superior laryngeal branch of the vagus nerve

31
Q

What innervates the sixth arch

A

the recurrent laryngeal branch of the vagus nerve

32
Q

The fourth arch gives rise to

A
Arch of the aorta,
right subclavian artery 
Original pulmonary arteries
Constrictors of the pharynx.
cricothyroid.
Levator veli palatine muscles
33
Q

The sixth arch gives rise to

A

Intrinsic muscles of the larynx

34
Q

First pharyngeal cleft develops into

A

External auditory canal.

Defects, develop into pre auricular cysts or fistulas

35
Q

The first pharyngeal pouch develops into

A

Eustacian tube

Middle ear cavity

36
Q

The second pharyngeal pouch develops into

A

Crypts of the palatine tonsil

37
Q

The third pharyngeal pouch develops into

A

Dorsal; Inferior parathyroid glands

Ventral; Thymus

38
Q

The fourth pharyngeal pouch develops into

A

Dorsal; superior parathyroid

Ventral; ultimobranchial body.

39
Q

Does the thyroid develop from any of the pouches

A

NO, it arises from a midline thyroid diverticulum

40
Q

What results from anomalies in thyroid development

A

Ectopic thryroid tissues and or cysts

41
Q

What syndrome is associated with anomalous dev of pouches 3 and 4

A

DiGeorge syndrome

deletion in the q arm of 22

42
Q

What is DiGeorge syndrome

A

hypoplasia of third and fourth pharyngeal pouch derivatives:
Ectopic or absent parathyroid, thymic or parafolicular thyroid tissue.
Heart defects (tetralogy of Fallot)
Hypoparathyrodism; low calcium and high Phosphorus in blood.
Cleft palate.
Small low set ears, wide-set eyes, long face, flattened groove in upper lip