Embryology of the Head, Face and Oral Cavity - Trump 2017 Flashcards
when does the central face start to develop?
4 weeks starting with the nasal placodes
The upper lip forms from what?
the medial nasal processes merging together as well as the maxillary processes merging to those
the primary palate forms from what?
the merger of the medial nasal processes
the secondary palate is formed from what?
the maxillary process of the first pharyngeal arch
WHat is cleft lip a result of? Is it bilateral or unilateral more often? When conditions need to be met for treatment to begin?
defective fusion of the medial nasal process with the maxillary process
80% are unilateral
Tx: lip, rule of 10: 10 weeks 10lbs 10gm %HM
what is cleft palate a result of? when do we treat it?
failure of the palatal shelves to fuse
treatment at about 1.5 years
Is it more common to have only Cleft palate or only Cleft Lip? HOw common is it to have both?
CP is more common but CL+CP is the most common
For Syndromic clefts what is most common (CL+CP or just CP or just CL)?
Cleft palate only is most common for syndromic patients
What is one syndrome we should know where Cleft palate is part of the syndrome? what are the other symptoms of this syndrome?
Pierre Robin sequence
CP
Mandibular MIcrognathia
Glossoptosis (downward displacement)
What are the factors involved in non syndromic cleft palate?
maternal alcohol or tobacco use
folic acid deficiency
corticosteroid use
anticonvulsant therapy
what causes lateral facial cleft?
lack of fusion of the maxillary and mandibular processes
what causes oblique facial cleft?
failure of fusion of the lateral nasal processes with maxillary process. commonly associated with Cleft Palate
what causes Median cleft of the upper lip?
failure of fusion of the medial nasal processes
what is the most common orofacial cleft?
oblique facial cleft
who are the top two races who have the highest prevalence of orofacial clefts?
Native Americans and Asians