Endo CE 2

Question 1

DM meds drug classes
7

Answer 1

biguanide
sulfonylurea
meglitinides
DPP-4 inhibitor
GLP-1
TZD
SGLT2

Question 2

biguanide ex

Answer 2

metformin

Question 3

sulfonylurea examples
3

Answer 3

glimepiride
glipizide
glyburide

Question 4

meglitinides ex
2

Answer 4

repaglinide
nateglinide

Question 5

DPP-4 inhibitor exs
4

Answer 5

alogliptin
linaglipitin (Tradjenta)
saxagliptin
sitagliptin (Januvia)

Question 6

GLP-1 ex
4

Answer 6

exenatide
liraglutide (Victoza)
dulaglutide (Trulicity)
semaglutide (Ozempic, Rybelsus)

Question 7

TZD ex
2

Answer 7

pioglitazone (Actos)
rosiglitazone (Avandia)

Question 8

SGLT2 ex
4

Answer 8

canagliflozin (Invokana)
dapagliflozin (Farxiga)
empagliflozin (Jardiance)
ertugliflozin (Steglatro)

Question 9

-glipitin is to

Answer 9

DPP4 inhibitors

Question 10

-glutide is to

Answer 10

GLP-1

Question 11

-glitazone is to

Answer 11

TZD

Question 12

-gliflozin is to

Answer 12

SGLT2

Question 13

liraglutide is to

Answer 13

victoza, GLP 1

Question 14

semaglutide is to

Answer 14

ozempic, rybelsus; GLP 1

Question 15

empagliflozin is to

Answer 15

jardiance; SGLT2

Question 16

SU MOA

Answer 16

potentiates insulin secretion

Question 17

cheap DM drug class

Answer 17

SU

Question 18

SU - watch out for
2

Answer 18

hypoglycemia
weight gain

Question 19

which drug class can cause weight gain

Answer 19

SU - glimepiride, glipizide, glyburide

Question 20

GLP 1 MOA

Answer 20

increases synthesis of insulin in response to BG rise

Question 21

GLP-1 comments
4

Answer 21

1. no hypoglycemia
2. weight loss
3. reduces CV risks
4. delayed gastric emptying

Question 22

not for HF

Answer 22

TZDs

Question 23

increased risk of fx

Answer 23

TZD

Question 24

SGLT2 inhibitor MOA

Answer 24

prevents reabsorption of renal glucose

Question 25

prevents reabsorption of renal glucose

Answer 25

SGLT2 inhibitors -gliflozin

Question 26

SLGT-2 inhibitor comments
5

Answer 26

1. weight loss
2. decreased BP
3. UTI
4. yeast infections
5. reduces CV risks

Question 27

increases risk of UTIs and yeast infections

Answer 27

SGLT-2 inhibitor

Question 28

preferred initial agent for pharm treatment of type 2 DM

Answer 28

metformin and weight management and physical activity

Question 29

where is metformin metabolized and excreted

Answer 29

metabolized - liver
excreted - kidneys

Question 30

what lab values would contraindicate use of metformin
2

Answer 30

decreased eGFR
elevated ALT, AST