Endocrine Physiology Flashcards

1
Q

Anterior pituitary

Acidophilic cells

A

GH, Prolactin

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2
Q

Anterior pituitary

Basophilic cells

A

FSH LH ACTH TSH MSH

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3
Q

Most abbundant cells in Ant. Pit?

A

Somatotropes 40%

Corticotropes 20%

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4
Q

This Ant. Pit hormone is not reduced by lesions in the pituitary stalk

A

Prolactin - has no releasing hormone, only INHIBITORY hormone - Dopamine

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5
Q

Treatment for Peripheral Diabetes insipidus

A

Thiazide diuretic

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6
Q

Treatment for SIADH

A

Demeclocycline (ADH antagonist)

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7
Q

Phenylalanine derivatives

A

Phenylalanine Tyrosine LDopa Dopamine NE Epinephrine Thyroxine Melanin

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8
Q

Tryptophan derivative

A

Tryptophan
Melatonin
Serotonin
Niacin

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9
Q

Inhibits Iodine trapping

A

Perchlorate

Thiocyanate

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10
Q

Steps inhibited by Propylthiouracil

A

Oxidation of iodine
Organification
Coupling

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11
Q

Thyroid hormones increase O2 consumption and BMR by what mechanism

A

Increases mitochondria and Na K ATPase pump activity

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12
Q

Tremors in Hyperthyroidism

A

FINE Muscle tremors

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13
Q

Diabetogenic hormones

A

Cortisol
GH
Glucagon
Epinephrine

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14
Q

Inhibits 11B hydroxylase in steroidogenesis

A

Metyrapone

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15
Q

Inhibits Cholesterol desmolase in steroidogenesis

A

Ketoconazole

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16
Q

Layers of Adrnal Cortex and their secretions

A

Z. Glomerulosa - Aldosterone
Z. Fasciculata - Cortisol
Z. Reticularis - Androgens

17
Q

Mechanism of elevation of BP by Cortisol

A

Increase vascular responsiveness to cathecolamine - Upregulates ALPHA receptors on arterioles - vasoconstriction

18
Q

GLUT trasport in Beta cells

A

GLUT 2

19
Q

Secreted by osteoblast to INHIBIT osteoclastic activity in hyperparathyroidism

A

Alkaline phosphatase

20
Q

Action of PTH on the intestines

A

NONE!!!

Vitamin D - increases calcium and phosphate reabsorption

21
Q

Positive Feedback involving hormones

A
  • Estrogen induced LH and FSH surge

* Oxytocin in Labor and Lactation