Endomembrane system Flashcards

1
Q

What is the function of the endomembrane system?

A

A group of membranous organelles with the task of modifying, packaging and transporting lipids and proteins and cellular digestion

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2
Q

What is the pathway for proteins?

A

Nucleus -> ER -> Golgi -> Cell membrane

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3
Q

What are the organelles part of the endomembrane system?

A

ER
Golgi apparatus
vesicles
Lysosomes
Vacuoles
Plasma membrane

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4
Q

What is the function of the RER

A

Protein synthesis: mRNA attaches to ribosome on RER and is translated in the lumen of ER. Folds and modifies newly built proteins.

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5
Q

What is the function of Lysosomes?

A

: acidic vesicles of digestive enzymes that breakdown & recycle food,debris, bacteria, etc

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6
Q

What is the Function of SER

A

Lipid synthesis and detoxifies drugs/posions

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7
Q

What is the function of the

A
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8
Q

Endomembrane system

A

A group of membrane-bound organelles inside a eukaryotic cell.
Includes many organelles that are interconnected by vesicles (little
membrane bubbles

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9
Q

Protein secretion

A

A process by which a substance is released into the environment

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10
Q

Nucleus

A

a rounded structure that contains & protects most of a eukaryotic cell’s DNA

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11
Q

Nuclear envelope

A

the double-membrane that surrounds the nucleus & acts as its barrier

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12
Q

Nuclear Pores

A

tiny “holes” in the nuclear envelope that allow entry/exit into & out of the
nucleus.

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13
Q

Nucleolus

A

a small dense structure inside the nucleus where ribosomes are assembled

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14
Q

ER

A

Endoplasmic Reticulum: membranous structures continuous with the nuclear
envelope.
- ER Lumen: the internal space/compartment of the ER.
1) Rough ER: closer to the nucleus with a rough, ribosome-coated surface.
- Newly built proteins fold & are modified in the rER lumen.
2) Smooth ER : further from nucleus with a smooth, ribosome-free surface.
- Synthesizes lipids & detoxifies drugs/poisons

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15
Q

Golgi Apparatus

A

Molecules synthesized in the ER (e.g. proteins & lipids) are transported by vesicles to the Golgi apparatus

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16
Q

Golgi Apparatus structure

A

stack of flat, membranous sacs (cisternae) that function as a“processing center.”

17
Q

Golgi Apparatus function

A

Receives vesicles, modifies vesicle contents, & repackages contents into vesicles for export.
* Receiving end of the Golgi = “Cis” end. - Shipping end of the Golgi = “Trans” end.
* Some vesicles shipped from Golgi apparatus can fuse with the cell membrane for secretion.

18
Q

Cell/Plasma membrane

A

It is a selective
* Made of a double layer of
phospholipids , with hydrophilic
and hydrophobic regions.
* Also has embedded proteins and
carbohydrate chains on the
outside.

19
Q

Cellular Digestion

A

Some of the organelles of the endomembrane system are more specialized
for cellular digestion. E.g. Digestion Lysosomes, Peroxisomes and Vacuoles

20
Q

Lysosomes

A

acidic vesicles of digestive enzymes that breakdown & recycle food,
debris, bacteria, etc.
- Primarily it is found only in animal cells & originate at the Golgi apparatus

21
Q

Peroxisomes

A

vesicles of enzymes that breakdown TOXIC compounds (converting it
to H2O2) & fatty acids.
- It is found in all eukaryotic cells
& originate at the rER .

22
Q

Vacuoles

A
  • Vacuoles are large vesicles derived from the ER and Golgi apparatus.
  • Vacuoles perform a variety of functions in different kinds of cells:
  • 1) Transport (vesicles); (2) Storage (food vacuoles);
    (3) Water balance (central vacuole & contractile vacuole)
23
Q

Types of Vacuoles

A
  • Food Vacuoles are formed by phagocytosis.
    *Central vacuoles, found in many mature plant cells, contain a solution called
    sap.
  • It is the plant cell’s main repository of inorganic ions, including
    potassium and chloride.
  • The central vacuole plays a major role in the growth of plant cells
  • Contractile, found in many freshwater protists, pumps excess
    water out of cells.
24
Q

Mitochondrion

A

Found in nearly all eukaryotic cells
* Have their own DNA
* Reproduce by binary fission
* Double membrane: a smooth outer
membrane and an inner membrane folded
into cristae
* The inner membrane creates two
compartments: intermembrane space
and mitochondrial matrix.

25
Q

Chloroplast

A

Chloroplasts, found in plants and
algae
* Contains green pigment
chlorophyll, as well as enzymes
and other molecules
* Chloroplast structure includes
-Thylakoids, membranous sacs,
stacked to form a granum
-Stroma, the internal fluid
* Convert light energy into chemical
energy.
* Own DNA
* Reproduce via Binary Fission