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Cell Biology > Endoplasmic Reticulum & Golgi Apparatus > Flashcards

Endoplasmic Reticulum & Golgi Apparatus Flashcards

1
Q

Where is the endoplasmic reticulum generally found?

A

Surrounding the nucleus

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2
Q

What does the ER form?

A

Hollow tubes and flattened sacs

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3
Q

What is the name given to the chambers of the ER?

A

Cisternae

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4
Q

What are the 5 functions of the SER?

A
  • Detoxification
  • Synthesis and storage of glycogen and glyceride
  • Steroid hormone synthesis
  • Phospholipid ane cholesterol synthesis
  • Calcium storage
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5
Q

What is the name given to ER in muscles?

A

Sarcoplasmic reticulum

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6
Q

What is the Golgi apparatus composed of?

A

Flattened discs; also called cisternae

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7
Q

How do the cisternae of the Golgi body communicate with ER and cell membrane?

A

Through the use of vesicles

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8
Q

What is material transported from the Endoplasmic Reticulum to the Golgi in?

A

Vesicles or tubules

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9
Q

What 3 specialised proteins coat the vesicles and area of membrane on the Golgi receiving the material?

A

Clathrin, COPI, COPII

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10
Q

What covers the outside of transport vesicles?

A

A protein coat

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11
Q

What are the 3 types of vesicle coats? What are each of their specific functions?

A
  1. Clathrin - formation of vesicles from cell surface and Golgi
  2. COP I - movement through Golgi complex
  3. COP II - formation of vesicles from ER to golgi
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12
Q

What are the 3 regions of the Golgi apparatus?

A

Cis face
Golgi stack (medial)
Trans face

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13
Q

What are the 3 functions of the Golgi apparatus?

A
  1. Modification and packaging secretions for release through exocytosis
  2. Renewal and modification of plasma membrane
  3. Delivery of material to other organelles
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14
Q

What are the two models of movement of vesicles through the Golgi called?

A
  • Vesicular transport

- Cisternal maturation

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15
Q

What is the vesicular transport model in the Golgi apparatus?

A
  • Suggests that the Golgi is static

Packages move through cisternae by vesicles

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16
Q

What is the cisternal maturation model in the Golgi apparatus?

A
  • Suggests that the Golgi is dynamic
    Cisternae progress through apparatus and mature from a cis cisternae to trans cisternae
    (New cisternae form at cis end)
17
Q

What is the current belief about the models of movement in the Golgi?

A

Combination of both

18
Q

How do vesicles reach the correct target?

A

SNAREs

Soluble N-ethylmaleimide

19
Q

What are the two types of SNAREs?

A
  • vSNARE - vesicle SNARE

- tSNARE - target SNAREs

20
Q

Where are the two types of SNAREs found?

A

vSNAREs are found in vesicle membranes

tSNAREs are found in target membrane

Cell Biology (21 decks)

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