Eosinophilic Oesophagitis Flashcards
1
Q
What is it?
A
Chronic immune/allergy mediated condition defined clinically by symptoms of oesophageal dysfunction, and pathologically by an eosinophilic infiltration of the oesophageal epithelium in the absence of secondary causes of local or systemic eosinophilia
2
Q
What is the role of eosinophils?
A
Eosinophils help promote inflammation, which plays a beneficial role in isolating and controlling a disease site, but sometimes inflammation may be greater than is necessary, which can lead to tissue damage
3
Q
What is the presentation?
A
Dysphagia + food bolus obstruction
4
Q
How is it diagnosed?
A
Endoscopy
5
Q
What is the management/treatment options?
A
Topical/swallowed corticosteroids
Dietary elimination
Endoscopic dilation
